Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Neoplasms, Experimental"”.
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Immune-Mediated Mechanisms of Phthisical and Non-Phthisical Intraocular Tumor Rejection
Although intraocular tumors reside in an immunoprivileged site where immune responses are suppressed, some tumors are rejected nonetheless. An example of this is the syngeneic adenovirus-induced (Ad5E1) tumor model. Intraocular tumors are rejected in one of two pathways: one that maintains normal …
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Anti-VEGF Therapy Modulates Immune Cell Infiltration and Function in Multiple Breast Cancer Models
Breast cancer is the most frequently diagnosed malignancy in women in North America. Advancements in standard treatment regimens have improved the overall outlook for breast cancer patients in recent years; however, 40,000 women a year succumb to this disease. Breast cancer is initiated when …
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The Role of Polyploidy in the Liver and Its Implications for Cancer Therapy
The description of liver polyploidy dates back to the 1940s, but its functional roles are still largely unknown. Numerous observations and studies have suggested that liver polyploidy may participate in multiple biological processes, including regeneration, stress response, and cancer. However, …
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IL-2 and Antisense TGF-B1 Gene Therapy of the H238 Tumor and Analysis of TGF-B Receptors
<p>Transforming growth factor-beta (TGF-p) belongs to a family of immunosuppressive cytokines, capable of regulating macrophages, T, B and NK cells. We have detected the TGF-p transcript being synthesized by H238 cells. This is herpes simplex-Type2 transformed murine fibrosarcoma cell line. The …