Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Needle biopsy"”.
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Multimodal spectroscopy : real-time diagnosis of breast cancer during core needle biopsy
… evaluation of tissue removed during core needle biopsy. Microcalcifications are used as targets to position biopsy devices, as they may indicate the presence of malignancy. Despite stereotactic guidance, needle biopsy fails to retrieve target microcalcifications in up to 15% of patients. …
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Design and development of systems and methods for interventional surgical robot
… procedure using guidewire/catheter and needle biopsy procedures are two common surgeries that are performed interventionally using image guidance. Inadequate visual and force feedback, while navigating surgical tools during endovascular (guidewire/catheter) procedures, elevates the risk …
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Platelet Function in Dogs with Chronic Liver Disease
… liver disease undergoing ultrasound-guided needle biopsy of the liver or laparoscopic liver biopsy and eighteen healthy age-matched control dogs. Methods: Prospective study. BMBT, CT using the PFA-100®, and vWF antigen were measured in dogs with chronic liver enzyme elevation undergoing …
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Towards force-correlated ultrasound volume elastography
… this technology could be used to replace needle biopsy in various diseases in which progression correlates with tissue stiffness, such as thyroid nodules or liver fibrosis and cirrhosis. Our method, unlike the inherently localized needle biopsy, allows for the assessment of tissue over a …
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Telomerase Activity in Prostatic Fluid and Tissue as a Marker for Prostate Cancer
… the detection of telomerase activity in prostate needle biopsy specimens and freshly collected prostatic fluid. Clinical application of a newly developed PCR-ELISA telomerase assay method is also evaluated. Multiple sextant needle biopsy specimens from 56 subjects and prostatic secretion specimens …
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Label-free multi-modal multiphoton imaging for real-time point-of-procedure assessment of needle biopsies
Needle biopsy (NB) is known as a standard clinical procedure for cancer diagnosis in humans and companion animals. There has been a rising concern about the time cost of the conventional histopathological assessment of the NB specimens. Therefore, a real-time point-of-procedure assessment method of …
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An MRI compatible manipulator for prostate cancer detection and treatment
… of prostate cancer. Following these tests, a needle biopsy is required to determine if a suspected tumor is benign or malignant. Currently, an ultrasound image is used to help guide a needle to the prostate and to the suspected region. However, ultrasound images are not of good enough quality …
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Fluorescence resonance energy transfer-based biosensors for monitoring prostate specific antigen
… screening, digital rectal exam, and prostatic needle biopsy. However, these methods lack the sensitivity to detect small lesions that occur in the early stages of cancer and metastasis. I propose a molecular imaging modality that provides a biochemical characterization of localized regions of …
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Risk Factors for Acute Prostatitis after Transrectal Biopsy of the Prostate
… acute prostatitis after transrectal prostate biopsy. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 923 transrectal ultrasound-guided needle biopsy of the prostate on 878 patients performed in our institution from June 2004 to May 2009. The indications for …
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A Comparison of Liver Biopsy Techniques in Dogs
Background: The liver biopsy technique in dogs that consistently provides samples adequate for accurate histopathologic interpretation and the variability of histopathology among lobes is unknown. Hypothesis: Liver biopsy specimens obtained via punch, cup biopsy, and 14 gauge needle biopsy would …
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A comparative cost analysis of the pathway to diagnosing lymphoma in a tertiary hospital, Western Cape, South Africa
… In tuberculosis (TB) endemic areas, a fine needle aspirate (FNA) is often used as the diagnostic tool of choice when trying to understand the underlying cause of lymphadenopathy (LAP), which can lead to delayed diagnosis of lymphoma (Antel et al., 2019). A significant gap exists in the lack …
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Genetic Evolution and Prognostic Determinants of Pancreatic Cancer On Longitudinal Liquid Biopsies
… recurrent metastatic PDAC, apart from a fine needle aspiration or a core needle biopsy performed for diagnosis. This precludes the opportunity for elucidating molecular underpinnings of cancer recurrence, chemoresistance, and therapeutic decision-making in advanced disease patients over the …
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International Academy of Cytology Yokohama System for reporting Breast Fine Needle Aspiration Biopsy (FNAB) cytology: A Retrospective Study in a Single South African Tertiary Institution
… of the triple assessment. Although core needle biopsy (CNB) is the gold standard and the preferred diagnostic modality, there is still a role for fine needle aspirate cytology (FNAC) in resource limited settings. The present study was conducted at Groote Schuur Hospital in Cape Town, …
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Imaging through optical multimode fiber: towards ultra-thin endoscopy
… needs such as deep-brain imaging, imaging-guided needle biopsy, and imaging-guided micro-surgery for new and scalable endoscope designs have motivated the concept of utilizing a single optical multimode fiber (MMF) as a stand-alone image conduit. MMF is fascinating as an optical waveguide …
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Target localization in MRI-guided prostate biopsy
… cancer is a worldwide health concern for men. Needle biopsy is the most definitive form of cancer diagnosis. Target-specific biopsies can be performed under magnetic resonance imaging (MRI) guidance. However, needle placements are often inaccurate due to intra-operative prostate motion and the …
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Krūties carcinoma in situ tipai, diagnostika, gydymas ir prognozė /
… The final diagnosis is confirmed by a fine-needle biopsy or surgery and histological analysis of the resulting tissue with immunohistochemical staining. The main aim of the treatment of carcinoma in situ is to remove the abnormal breast tissue cells and reduce the risk of disease recurrence …
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Microfluidic tools for molecular analysis and engineering
… of patient tissue, such as the amount from a needle biopsy. In order to perform so many different assays it is paramount that we develop high sensitivity methodologies, such that we can gain an understanding of the patient's physiology without causing much discomfort in gathering large amounts …
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Organ Viability Assessment in Transplantation based on Data-driven Modeling
… assessment methods are visual inspections and biopsy. Yet both methods are subjective: the assessment accuracy depends on the evaluator's experience. Moreover, repeating biopsies will potentially damage the organs. To reduce the waste of donor organs, online non-invasive and quantitative organ …
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Double volumetric navigators for real-time simultaneous shim and motion measurement and correction in Glycogen Chemical Exchange Saturation Transfer (GlycoCEST) MRI
… largely relies on tissue sampling methods via needle biopsy. However, muscle biopsies are invasive and limit the frequency of measurements and the number of sites that can be assessed. Non-invasive methods for quantifying glycogen in vivo are therefore desirable in order to understand the …
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Selected exercise and skeletal muscle characteristics of African distance runners
… muscle characteristics were determined by needle biopsy of the vastus lateralis muscle. Skeletal muscle enzymes citrate synthase, phosphofructokinase, 3-hydroxyacyl CoA dehydrogenase, hexokinase and carnitine palmityl transferase were assayed spectrophotometrically. Skeletal muscle …
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