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Showing 1 to 7 of 7 for “"Nedd4-2"”.

  1. The regulation of neuronal excitability by epilepsy-associated gene Nedd4-2

    Zhu, JiuheUniversity of Illinois at Urbana-Champaign2020

    … developmentally down-regulated gene 4-2, Nedd4-2, was specifically noted. Furthermore, three missense changes in Nedd4-2 have also been identified in families with epilepsy. Nedd4-2 gene encodes a ubiquitin E3 ligase that has high affinity toward binding and ubiquitinating membrane …

    uiuc Repository record

  2. Modulation of in vitro and in vivo NGFmediated functions in response to TrkA ubiquitination by Nedd4-2

    Tao, Yu2012

    salamanca Repository record

  3. Mechanisms of translational control by the ubiquitin E3 ligase neural precursor cell expressed developmentally down-regulated gene 4-like, Nedd4-2

    Lodes, Daphne ElizabethUniversity of Illinois at Urbana-Champaign2022

    Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-05-01

    uiuc Repository record

  4. The role of Ubiquitin ligases Nedd4-1 and Nedd4-2 in the brain and their crosstalk with alpha-synuclein and other dementia-related proteins

    Conway, James2024

    … cell-expressed developmentally derived 4 (Nedd4) is a family of proteins of which some members have been shown to target α-synuclein for breakdown through ubiquitination, both in cellular models, and in fly and rat PD models. It is therefore of interest to research the effect of deleting …

    plymouth Repository record

  5. Hormone-induced expression of the epithelial sodium channel in human airway cells

    Ismail, NoorUniversity of Dundee2013

    … and thus inactivating, a ubiquitin ligase (Nedd4-2), that normally mediate the withdrawal of ENaC subunits from the plasma membrane. Protein kinase A (PKA) may contribute to this control mechanism by also phosphorylating Nedd4-2. In order to clarify the way in which these pathways contribute …

    dundee Repository record

  6. WNK Family Kinases and the Regulation of Ion Flux

    Heise, Charles John2010

    … developmentally downregulated protein 4-2, or Nedd4-2.

    utswmed Repository record

  7. Interplay between collapsin response mediator protein 2 (CRMP2) phosphorylation and sumoylation modulates NaV1.7 trafficking

    Dustrude, Erik Thomas2015

    … internalization involving E3 ubiquitin ligase Nedd4-2 as well as endocytosis adaptor proteins Numb and Eps15. Collectively, my findings identify a novel mechanism for regulation of Nav1.7.

    iupui Repository record