Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Near UV light"”.
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Repair in Ehrlich Ascites Tumor Cells
… (EAT), using ionizing radiation, far ultraviolet light (254 nm) or near UV light (365 nm) in combination with 8-methoxypsoralen. UDS was scored by grain counts in autoradiographs following the incorporation of tritium-labelled thymidine. The amount of UDS after each of these agents was expressed …
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Reactions of 4-chloro-2,6-dimethoxypyrimidine and 2-chlorothiazole with carbanion nucleophiles
… S<sub>RN>1 mechanism upon photostimulation with near-UV light to give good yields of substitution products resulting from displacement of chloride ion. Both photostimulated and dark reactions of 4-chloro-2,6-dimethoxypyrimidine (1) with the carbanions of acetonitrile and propionitrile proceed …
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Engineering a Photo-Control Mechanism for RNA Interference
… species that blocks bioactivity until exposed to near UV-light. This work demonstrates that fully-2’-fluorinated nucleic acids (FNAs) can elicit RNAi and that these effectors are resistant to sugar-specific enzymatic digestion. 1-(4,5-dimethoxy-2-nitrophenyl)diazoethane (DMNPE) was used to cage …
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Novel Bio-Imaging Techniques Based on Molecular Switching
… two original molecular states actually adds nonlinearity into the linear fluorescence process, which empowers fluorescence microscopy additional imaging capabilities. Herein, we developed four distinct new imaging techniques by taking advantage of this molecular switching mechanism: dark state …
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Next-Generation Oligonucleotide Probes For Transcriptome In Vivo Analysis (tiva)
… In Vivo Analysis (TIVA), utilizes a light-activatable oligonucleotide probe to offer fine spatio-temporal control of mRNA capture. TIVA probes are highly modified RNA hairpins or loops incorporating a poly(U) “capture” sequence complementary to the poly(A) tail of mRNA, as well as a …
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Photodegradation of peptides and proteins by near UV and visible light
… by aggregation and oxidation of mAbs. While near UV and visible light can lead to the oxidation of mAbs, no concise mechanism has been established for the photo-oxidation of mAbs. Here, we evaluated the formation of reactive species by carboxylic acid buffer-Fe3+ complexes, which can absorb …
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A study of various nucleophiles in aromatic SRN1 reactions
… and heteroaromatic substrates. Upon 5-25 min of near-UV irradiation, the carbanions of 2-benzyl-4,4-dimethyl-2-oxazoline, ethyl phenylacetate, t-butyl acetate, N,N-dimethylacetamide and dimethyl methylphosphonate underwent reactions with both 2-bromopyridine and iodobenzene in an …