Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Near Infrared Fluorescence Imaging"”.
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Leveraging Antibodies for Positron Emission Tomography and Near-Infrared Fluorescence Imaging of Cancer
… explore the synthesis and use of antibody-based imaging agents in preclinical models of cancer. This work can be described as two-fold. In the first part, we investigated how the use of a glycans-specific bioconjugation strategy affects Fc gamma RI binding and why it results in improved <em>in …
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New optical materials containing isobenzofuran
… synthetic route to integrate isobenzofuran into near-infrared donor-acceptor type fluorophores. These dyes, the IBF-NIADs, exhibit red-shifted absorption and emission over corresponding isothianaphthene containing dyes, thus highlighting the effective proquinoid nature of isobenzofuran. With the …
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Development and Evaluation of Paclitaxel-Loaded Liposomal Formulations for Targeted Drug Delivery to Breast Cancer
… bearing MDA-MB-231 breast cancer using near infrared fluorescence imaging showed that the accumulation of tumor vasculature targeted long-circulating liposomes (LCL) in the tumor was significantly less than non-targeted LCL at 48 h. The accumulation of these liposomes in the peritoneal …
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Goggle Augmented Imaging and Navigation System for Fluorescence-Guided Surgery
… lymph node visualization.</p> <p>Conventional imaging modalities such as x-ray computed tomography, positron emission tomography, magnetic resonance imaging, and ultrasound are excellent for preoperative cancer diagnosis and surgical planning. However, they are not suitable for intraoperative …
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Development and Evaluation of Brain Tumor Targeted Liposome Delivery System for Paclitaxel
… effects of PEG, enhanced target accumulation. Near infrared fluorescence imaging demonstrated that these liposomes accumulated selectively in flank tumors with tumor targeting index of 10.59 ± 1.08. Paclitaxel incorporated into the targeted liposomes delayed tumor growth by 7.7 days in 5 doses …
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Src Homology 2 Domain-Containing 5’-Inositol Phosphatase-2 (Ship2) Is An Effector of Lymphatic Dysfunction
… to lack of molecular knowledge and inadequate imaging techniques to safely, rapidly and non-invasively visualize the lymphatics, lymphedema remains under diagnosed and progresses to the irreversible stage if not diagnosed early.</p> <p>Candidate gene studies have identified a myriad of genes …