Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Natural products--Synthesis"”.
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Complex botanical natural products: Synthesis of cephalotaxus esters and of the C19-diterpenoid skeleton of aconitum and delphinium alkaloids
… using a β-lactone acyl chain surrogate in the synthesis of anhydroharringtonine, deoxyharringtonine, homodeoxyharringtonine, and homoharringtonine is described. The natural esters as well as several non-natural analogues were tested against various human cancer cell lines not previously …
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Strategic Applications of Tandem Reactions in Complex Natural Product Synthesis: Rapid Access to the (Iso)Cyclocitrinol Core
… Professor James Leighton and myself toward the synthesis of the tetracyclic core of a class of steroidal natural products known as the cyclocitrinols. Our initial work in this area was performed on racemic model systems in order to validate our ring contraction-Cope rearrangement strategy. Novel …
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Synthetic Studies of the Yunnaneic Acids
… acid B are also described, which resulted in the synthesis of several novel, non-natural structures.
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Strategies and Tactics for the Synthesis of Polycyclic Alkaloids
The myrmicarin family of oligomeric natural products comprises one of the most ornate collections of polycyclic alkaloids known. The structural characterization of their unique scaffolds was accomplished through elegant spectroscopic studies. Furthermore, the synthesis of these alkaloids has …
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Synthesis of Marine Chemicals and Derivatives as Potential Anti-Cancer Drugs.
<p>Two natural marine compounds, 3-bromo-4,5-dihydroxybenzaldehyde <b>2</b> and 2,3-dibromo-4,5-dihydroxybenzaldehyde <b>5</b> together with two novel derivatives, 3-bromo-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxybenzaldehyde <b>3</b> and 1-bromo-2,3-dimethoxy-5-nitrooxy-methylbenzene <b>9</b>, …
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Towards the automation of small molecule synthesis: The development of an impact-prioritized list couplings and blocks for building block assembly of most linear natural products
… we report an en masse analysis of most linear natural products which has revealed an impact-prioritized list building blocks that would provide a Lego kit for the iterative synthesis-based access to greater than 75% of the chemical space occupied by these 100k linear natural products. We also …