Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Natural genetic variation"”.
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Natural Genetic Variation Affecting Calcium Homeostasis
… regulator, 1,25(OH)2D, are affected by both genetic and environmental factors.</p> <p>However, the genetic architecture of these phenotypes has not been carefully studied in a controlled environment. Using genetically characterized mouse models in a controlled environment the studies in this …
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Characterising natural genetic variation in dynamic photosynthesis and photoprotection in sorghum
… photosynthetic efficiency-related traits, but variation in photoprotective capacity within crop species, particularly those utilizing the C<sub>4</sub> photosynthetic pathway, is not yet well-characterized. The aim of this research project was to determine the genetic underpinnings of …
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Characterizing natural genetic variation in photosynthetic efficiency across 44 accessions and five subpopulations of oryza sativa
… against the control IR64, confirming a wealth of natural variation that might be exploited to improve photosynthetic efficiency in cultivated rice. Examining existing natural genetic variation allows superior genotypes and traits to be identified, aiding in targeted plant improvement through …
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Natural genetic variation and gene expression patterns underlying lateral shoot (tiller) development in barley (Hordeum vulgare L)
… completed to gain a better understanding of the genetic control of tiller development. One focused on characterizing natural phenotypic and genetic variation in tiller number throughout development in a large, diverse germplasm collection; and the second focused on identifying meristem-specific …
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Natural Variation and Gene Expression in the Male Courtship Progression of Drosophila Melanogaster
Natural genetic variation in the temporal sequence of male courtship behavior can be one target of selection. The goals of this research were to identify variation in the sequence of male behavior using a natural population, and investigate the genetic underpinnings of this variation. A new, …
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Strain-resolved transcriptomics: exploring functional heterogeneity of the gut microbiota in health and disease
… 335 non-IBD patients), we first constructed phylogenetic trees for over 250 bacterial species using the single nucleotide variants within essential housekeeping genes, enabling the identification of bacterial strains. Next, we devised a statistical approach to assign mRNA reads to these strains, …
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Natural Variation in Arabidopsis thaliana Growth in Response to Ambient Temperatures
… Trait Loci (QTL) responsible for the natural genetic variation of hypocotyl length in response to ambient temperatures. The Arabidopsis thaliana accessions were phenotyped for hypocotyl length at 12°C, 17°C, 22°C and 27°C ambient temperature environments and substantial genetic …
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The evolution and genetics of virus resistance in Drosophila
… Much of the resistance is determined by genetic factors, however, it is unclear what genetic factors promote resistance to parasites. In this thesis, I used Drosophila melanogaster as a model system to study the genetic basis of resistance against RNA viruses. To understand the genetic …
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Investigating the effects of genetic variation on heterochromatic crossover events in Arabidopsis thaliana
… events result in the reciprocal exchange of genetic material between homologous chromosomes during meiosis. Numerous genetic and environmental factors have been shown to influence the meiotic recombination landscape in many different species. My thesis uses the model plant *Arabidopsis …
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Integrating bioinformatic approaches to promote crop resilience
… impacts are predicted to become even greater. Natural genetic variation, long used by traditional plant breeders, holds great promise for adapting high performing agronomic lines to these stressors. Yet, efforts to bolster crop plant resilience using wild relatives have been hindered by time …
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Natural genetic and phenotypic variation for aging
… why and how we age, we must explore the variation of aging in populations, both genetically and phenotypically. Historically, two main approaches have been used to try and understand how and why we age, including evolutionary and mechanistic approaches. Evolutionary approaches to studying …
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Physiological Bases and a Novel Genetic Determinant of Water-Use Efficiency (WUE)
… loss, is a heritable but complex trait, the genetic basis of which is largely unknown. We utilized diverse accessions of the halophyte <em>Eutrema salsugineum </em>to ultimately identify a novel genetic determinant of WUE. <em>E. salsugineum</em> accessions from locations with low water …
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Understanding the Effects of Genetic Variation on Osmo-adaptation Dynamics Across S. cerevisiae using Bulk Segregant Analysis and Whole Genome Sequencing
… few studies have focused on the effects of genetic variation. Understanding how genetic variation affects molecular pathways and their dynamics, which translates to variation in cellular and organismal phenotypes, is a key step towards understanding important phenomena such as complex gene …