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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"Natural antimicrobial"”.
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Natural antimicrobial nanomaterials for food packaging applications
… their shelf-life. To address this challenge, natural antimicrobial nanomaterials (NAMs) can be used to inhibit food spoilage microorganisms and extend the shelf-life of food products. Several of the most effective NAMs include: antimicrobial polysaccharides (chitosan (CS)), plant essential …
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Development of Multi-layer Films Containing Natural Antimicrobial Agents
… comprising an inner coating layer containing natural antimicrobial (AM) agents were developed. Volatile essential oils obtained from plant extracts including carvacrol, linalool and methylchavicol were used as the active AM agents in the coating layer. The amount of natural AM agents and the …
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Formation, Characterization and Stability of Natural Antimicrobial-Cyclodextrin Complexes
As a response of the need for a natural antimicrobial to replace sodium benzoate's use as a preservative in beverages, twenty eight compounds known to have antimicrobial activity were evaluated to quantify their solubility. Twenty three of the compounds evaluated are components of plant essential …
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Incorporation of natural antimicrobial agents into starch-based material for food packaging
Antimicrobial (AM) films comprising of thermoplastic starch (TPS) and a commercial aliphatic polyester blended with thermoplastic starch (APTPS) were prepared and their properties, release of AM agents, and AM efficacy was studied in laboratory media and on a real foodstuff (Cheddar cheese). The AM …
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The discovery of a novel bioactive peptide, QUB-1036, from the defensive skin secretion of Pelophylax kl. esculentus
Gene-coded antimicrobial peptides (AMPs) are a great source of natural antimicrobial agents and good models for the design of new generation antibiotics. In the meantime, a large number of AMPs have been isolated and characterised from different amphibian species due to their special skin structure …
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Engineering membrane-selective antibiotic peptides to combat multidrug resistance
… that mandates new drug development strategies. Natural antimicrobial peptides (AMPs) have been long-recognized as a potential source of bacteriolytic drugs, but the shortcomings of non-specific membrane toxicity, proteolytic instability, and in vivo toxicity have stymied their clinical …
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Pathogen Membrane Interactions
… electrostatic and hydrophobic interactions. Natural antimicrobial peptides and their synthetic derivatives are amphipathic molecules with broad-spectrum antimicrobial activity, but the underlying mechanism needs clarification. We systematically investigated interactions between model …
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Characterized analysis of peptide QUB-1433 from the skin secretion of the dark-spotted frog (Pelophylax nigromaculatus)
… frog skin have been widely discovered to exhibit antimicrobial and anticancer activities. Since the antibiotic resistance has become a severe difficulty in modern therapeutic treatment, many of them have been developed into clinical application for the treatment of microbial infection and …
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The Design of Antimicrobial Detachable Thin Films for the Study of Hepatic Infections
… It is imperative to explore broad spectrum antimicrobial approaches. In this work, we modified collagen/hyaluronic acid polyelectrolyte multilayers (PEMs) with the natural antimicrobial peptide, LL-37 to study hepatic infections. LL-37 was physisorbed and covalently linked to the surface of …
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Characterization of alpha-cyclodextrin inclusion complexes with trans-cinnamic acid in an acid-based beverage system
In response to a need for a natural antimicrobial to replace sodium benzoate, cinnamic acid was chosen. Due to cinnamic acid's solubility issues, α-cyclodextrin was used as a host molecule to form an inclusion complex with the cinnamic acid molecule. The cinnamic acid: α-cyclodextrin inclusion …
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Comparative Phenotypic and Transcriptional Differences of Campylobacter jejuni When Challenged with Low Molecular Weight Chitosan
… hurdles are used in the food industry, including natural products such as modified atmosphere and salt. Other natural antimicrobials are shown to possess antibacterial activity. Chitosan, a natural antimicrobial, has promising uses in food production. However, little is known about the …
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Antimicrobial effects of naturally occurring compounds against microorganisms relevant to food safety
… Commission has banned the growth promoting antimicrobials in food animal production since Jan 2006. Research on the potential application of naturally occurring compounds in the food industry has recently gained increasing attention.<br/><br/>This study aim at evaluating the antimicrobial …
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Design, synthesis and mode of action of short biphenyl and anthranilamide cationic peptidomimetics
Antimicrobial resistance is a major worldwide threat to public health and there is an urgent need for the development of novel antibacterial agents. This research project focused on the development of short cationic peptidomimetics that employ 3'-amino-[1, 1 '-biphenyl)-3-carboxylic acid and …
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Discovery and design of novel bioactive peptides from amphibian skin secretion
… techniques were used to obtain the sequences of natural antimicrobial peptides and their synthesis was achieved using solid-phase synthesis (SPPS). In addition, the peptides were purified and identified by high-performance liquid chromatography (HPLC) and MALDI-TOF MS, and their biological …
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Conversion of triacylglycerols into monoacylglycerols by penicillium roquefortii
… together with free fatty acids may be part of a natural antimicrobial system in high pH foods such as blue mould-ripened cheese where growth of foodborne pathogens such as Listeria monoGytogcnes can be a problem from time to time
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Allyl isothiocyanate reduces Salmonella enterica Michigan and Listeria monocytogenes on the surface of whole cantaloupe (Cucumis melo L.)
… the use of allyl isothiocyanate (AITC; a natural antimicrobial) to reduce populations of S. enterica Michigan and L. monocytogenes on the surface of cantaloupe. Fifty μl of S. Michigan or L. monocytogenes was inoculated onto whole ‗Athena‘ or ‗Hales Best Jumbo‘ (‗HBJ‘) cantaloupe fruit in …
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Development and characterisation of biosynthetic hydrogels for wound management applications
… (ATCC 23770) and subsequently loaded with antimicrobial healing agents, were characterised for their wound healing properties. Loading parameters were optimised based on experimental findings. Natural bioactive materials with wound healing properties such as curcumin are attracting interest …
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Identification, characterization and bioevaluation of a bioactive peptide from the skin secretion of the Chinese forest frog
… problem that needs to be solved in the world. Antimicrobial peptides are considered to be a new treatment scheme that is difficult to form drug resistance due to their special membrane antibacterial mechanism. Amphibian skin secretion was found to be an ideal source of antimicrobial peptides, …
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CRABS & ‘CROBES: THE TRIPARTITE RELATIONSHIP OF A HOST, PARASITE, AND THEIR RESPECTIVE MICROBIOMES
… Pseudoalteromonas species, which provide natural antimicrobial defenses, while uninfected crabs were mainly comprised of Rhodobacteraceae, commonly associated with photo- and chemoautotrophy. To develop the methodology for the second part of the research, modified Kirby-Bauer disk …
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Molecular cloning, structural characterisation and functional study of peptides from amphibian skin secretion
… of biologically-active compounds, such as antimicrobial peptides (AMPs), anticancer peptides and trypsin inhibitors. Several kinds of AMPs, isolated and characterised from the skin of amphibians, have been studied by researchers to provide novel kinds of drugs and pharmacological agents for …
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