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Showing 1 to 3 of 3 for “"Native MS"”.

  1. Investigation of mass spectrometry approaches for aiding fragment-based drug discovery

    The use of mass spectrometry (MS)-based techniques to study protein structure dynamics is a relatively new field, with seminal developments such as nanoelectrospray ionization (nano-ESI) and traveling-wave ion mobility-mass spectrometry (TWIM-MS) MS being introduced only around twenty-five and …

    cambridge Repository record for Investigation of mass spectrometry approaches for aiding fragment-based drug discovery (opens in a new tab)

  2. New Mass Spectrometry Approaches to Investigate Proteins and Protein Interactions

    Mass spectrometry (MS) is essential for understanding the composition, structures, and interactions of proteins. There are various forms of MS that can be used to obtain valuable information about proteins and protein interactions. In native MS, intact protein ions are generated from a solution …

    washington Repository record for New Mass Spectrometry Approaches to Investigate Proteins and Protein Interactions (opens in a new tab)

  3. Biophysical Studies of Protein Assemblies

    … rate constants of two contrasting model systems. The lack of pre-formed binding interfaces—a consequence of disorder—might preclude electrostatic acceleration from complementary patches. By looking at the role of the sequence, many studies have taken a protein-centric approach to understanding …

    cambridge Repository record for Biophysical Studies of Protein Assemblies (opens in a new tab)