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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Naringenin"”.
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Effects of naringenin on glucose uptake in L6 skeletal muscle cells
… insulin resistance in vitro and in vivo. Naringenin, a citrus flavonoid with structural similarities to resveratrol, is reported to have antioxidan.t, antiproliferative, anticancer, and anti-inflammatory properties. Effects on glucose and lipid metabolism have also been reported including …
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Effects of Chemical and Enzymatic Modifications on Starch and Naringenin Complexation
<p>Naringenin is a flavanone naturally present in grapefruit and tomato skin, which has been demonstrated to have health benefits. However, because of the low water solubility and bioavailability, naringenin applications are limited. Starch inclusion complexes have been shown to improve the …
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The grapefruit flavonoid naringenin as a Hepatitis C virus therapy : efficacy, mechanism and delivery
Hepatitis C virus (HCV) infection accounts for approximately 40% of chronic liver disease in the United States and results in an estimated 8,000-10,000 deaths annually. Simulations suggest that in the next decade morbidity and mortality associated with HCV infections will result in approximately …
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Modulatory Effects of Citrus Flavonoids Towards the Metabolism and Mutagenicity of Environmental Carcinogens
… citrus. These flavonoids were diosmin, naringin. naringenin, rutin, and quercetin. Our results suggest that naringenin and quercetin were the strongest inhibitors of the metabolic activation of NNK, while diosmin, naringin, naringenin, and rutin each demonstrated protective effects toward …
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Cоx-2 inhibitоrѕ in Оeѕоphаgeаl Cаncer
… a naturally occurring Cox-2 inhibitor and naringenin, an antioxidant. With this validation, it would be possible to measure the dietary intake of these compounds in an individual’s diet and recommend dietary changes by conducting further studies. Flavonoid study: Methods: A food frequency …
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Dynamic Regulation of Metabolic Flux Using Orthogonal Quorum Sensing
… production of the valuable natural products of naringenin and bisnoryangonin in Escherichia coli. To our knowledge, the resulting regulations led to the highest extracellular titers at the flask scale with a final naringenin titer of 1251.2 +/- 59.6 mg/L and a bisnoryangonin titer of 597.7 +/- …
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Investigations on the effects of Typha capensis on male reproductive functions
… cell lines to bioactive compounds (Quercetin and Naringenin) isolated from T. capensis rhizomes. Part 1: TM3-Leydig cells and LNCaP cells incubated with different concentrations of crude aqueous extract of T. capensis rhizomes (0.01, 0.02, 0.1, 1, 10 and 100 µg/ml) and control (without extract) …
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Using Dictyostelium discoideum to develop flavonoid therapeutics for polycystic kidney disease: the role of MATE transporters
… are considered in the light of the evidence for naringenin specifically inhibiting cyst-forming kidney disease. D. discoideum is a valuable model organism for studying both cell biology and processes in human health and disease. Its genome was sequenced some years ago and the amoeba is well …
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Development of quorum-sensing circuits for metabolic flux control in Escherichia coli
… components. To address major limitations in the naringenin and salicylic acid pathways, one module was used to delay transcription of key heterologous genes to overcome enzyme inhibition and growth burden while the second module controlled expression of CRISPRi components to silence competing …
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Chemical Modification of Alginates in Organic Media
… of the poorly water soluble flavonoid naringenin.
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A study of the toxicological properties of propolis samples from Europe and Saudi Arabia and of their biological activity against protozoa
… namely 4', 7-Dimethoxykaempferol (12) and Naringenin 4', 7-dimethyl ether (13), and three compounds from a Saudi propolis sample: Hesperetin-7-methyl ether (14a), Sakuranetin (14b) and Lupeol (15). Both the crude extracts and isolated compounds displayed variable activity against the range …
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The Chemistry of Flavonoids in Model Beverages and Human Milk
… epigallocatechin gallate (215.1-2364.7 nmol/L), naringenin (64.1-722.0 nmol/L), kaempferol (7.8-71.4 nmol/L),hesperetin (74.8-1603.1 nmol/L), and quercetin (32.5-108.6 nmol/L) were present in human milk samples with high inter/intraindividual variability. With the exception of kaempferol, the …
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Characterization of chalcone synthase genes in red raspberry cultivar (rubus idaeus)
… PKS1 gene sequence, currently identified as Naringenin chalcone-PKS. The alignments of assembled sequences also strengthened the similarities between these two BACs both at nucleotide and amino acid sequences. All four PKS/CHS gene regions found in the both BACs presented being multiple …
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QTL discovery for Japanese beetle resistance in aphid-resistant germplasm, stacking aphid-resistant genes, and metabolite profiling studies in soybean
… of Daidzein, Genistein, Glycetein, Kaempferol, Naringenin, and Quercetin were found in damaged and un-damaged leaflets. Higher abundances of flavonoids were found in damaged leaflets of LD05-16060. It appears that differential susceptibility to Japanese beetle observed between LD05 and E06906, …
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Investigating the modulation of oral drug absorption using in vitro models
… be inhibitors of CYP3A4 yet neither naringin nor naringenin had any significant effect at concentrations found in grapefruit juice. Of the other (non-grapefruit) flavone derivatives tested, hesperidin, found in orange juice, had no significant effect, kaempferol and rutin also had no effect while …
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The application of actinobacterial extracts for plant growth promotion
… clusters encoding ectoine, siderophores, and naringenin biosynthesis were identified, suggesting potential evidence for the observed drought tolerance in plant growth trials. Overall, the findings of this study revealed that medicinal plants are a potential pool of untapped microbial diversity …
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Investigation of the role of root flavonoids in the interaction of chickpea with nitrogen-fixing symbionts and parasitic nematodes
… plants. They are 2'-O-methylisoliquiritigenin, naringenin, formononetin, 7,4'-dihydroxyflavone, liquiritigenin, isoliquritigenin and kaempferol. In contrast, nematodes induced 6,7,4'-trihydroxyisoflavone, afromosin and morin. Interestingly, most of these flavonoids were not induced when both …
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Investigation of the role of root flavonoids in the interaction of chickpea with nitrogen-fixing symbionts and parasitic nematodes
… plants. They are 2'-O-methylisoliquiritigenin, naringenin, formononetin, 7,4'-dihydroxyflavone, liquiritigenin, isoliquritigenin and kaempferol. In contrast, nematodes induced 6,7,4'-trihydroxyisoflavone, afromosin and morin. Interestingly, most of these flavonoids were not induced when both …
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Vergleichende molekulare und physiologische Untersuchung von Östradiol, drei Flavanonen und eines Heilpflanzenextrakts auf Östrogen-regulierte Endpunkte in Uterus und Gefäßsystem
… synthetisierten Flavanone 6-(1,1-Dimethylallyl)Naringenin (6DMAN) und 8-Prenylnaringenin (8PN), die ursprünglich in Pflanzen identifiziert wurden. 7-Oxyprenylnaringenin-4'-Azetat (7OPN) ist ein weiteres Mitglied dieser Stoffgruppe, zu dem jedoch bisher noch praktisch keine Daten vorlagen. …
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cDNA Cloning, Expression and Characterization of a Putative Glucosyltransferase (GT) from Grapefruit (<em>Citrus paradisi</em>) Leaves.
<p>Flavonoids are plant secondary metabolites that are integral to our lives. Grapefruits are well-known for production of unique glucosylated products and the enzymes responsible are UDP-glucose:glucosyltransferases (GTs). The objective of this research was to obtain full-length clones of putative …
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