Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"Nanosensors"”.
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Assessment of ion-selective optical nanosensors for drug screening applications
… An ion-channel assay system using optical nanosensors has recently been developed. This high-throughput, high-content system improves on the existing patch clamp and fluorescent dye technologies that presently dominate the ion-channel screening market. This paper introduces the nanosensor …
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Protease activated nanosensors for the noninvasive diagnosis of community-acquired pneumonia
… to create breath-based volatile activity-based nanosensors (vABNs), and demonstrated that we that could detect pneumonia within 15 minutes of administration. Altogether, these nanosensors enable urine and breath-based detection of CAP, and constitute a means of diagnosing pneumonia that is …
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MMP-7 nanosensors for urine-based detection of chemotherapy-induced senescence and pulmonary fibrosis
Lung cancer is a debilitating disease with poor survival rates, causing nearly 1.7 million deaths annually. Senescence is a cellular response to irreparable damage consisting of the implementation of a stable cell cycle arrest and pro-inflammatory activity via the secretion of senescence-associated …
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Embedded Nanosensors for defect identification using flexible, optically transparent, deformation responsive wrinkled Single Walled Carbon Nanotube meshes
Most structures such as buildings, pipelines carrying natural gas, nuclear plant cooling tanks and so forth are made of concrete. In vivo detection of the onset of cracks and voids in these concrete structures have many barriers and neglecting those could lead to failure of structures causing loss …
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Construction and Performance Optimization of Bioconjugated Nanosensors for Early Detection of Breast Cancer and Pro-inflammatory Diseases
<p>In recent years, nanosensors have emerged as a tool with strong potential in medical diagnostics. Single-walled carbon nanotube (SWCNT) based optical nanosensors have notably garnered interest due to the unique characteristics of their near-infrared fluorescence emission, including tissue …
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Noninvasive disease diagnostics using engineered synthetic urinary biomarkers
… existing diagnostics, we modified our protease nanosensors to release ligand-encoded reporters compatible with clinical ELISA and paper-based lateral flow assays. These detection techniques enable simple and inexpensive quantification of our synthetic disease reporters by ensuring compatibility …
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Protease activity sensors for monivasive diagnosis and monitoring of pulmonary diseases
… end, our group has developed "activity-based nanosensors", which detect dysregulated protease activity at the site of disease and release a reporter that can be measured in the urine. Because proteases are implicated in multiple diseases, including cancer, activity-based nanosensors have the …
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Immobilization of Inorganic Nanoparticles on Responsive Polymer Brushes
… nanoassemblies in the fabrication of nanosensors. The design of fabricated nanosensors is based on the modulation in the interparticle distance of immobilized nanoparticles due to swelling/deswelling of underlined polymer brushes in response to some external trigger.
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Optimization of Optical Nanosensor Response for the Detection of Anthracyclines Using a Binary Machine Learning Classifier
… analyzing patterns in responses of fluorescent nanosensors to a class of chemotherapeutics and therefore detecting the specific anthracycline. We anticipate future work in developing multi-purpose nanosensors that monitor the pharmacokinetics of active pharmaceutics to decrease toxicity while …
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Synthesis and characterization of Carbon Quantum Dots, ZnO and Magnetic Nanoparticles. New Analytical Applications
… aim to use them as lubricant additives and as nanosensors. Firstly, the synthesis, functionalization and characterization using different analytical tools (XRD, FTIR, TEM, HRTEM, NMR, and Spectrophotometry UV-Vis) were performed. As a result, magnetic nanoparticles functionalized with …
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Large area plasmonic nanostructures design, fabrication and characterization by laser
… sensing sensitivities of plasmonic bio/chemical nanosensors. This thesis involves theoretical and experimental studies of optical properties and near-field enhancement from random nanoparticles, quasi-ordered nanoparticles, and periodic arrays of nanostructures, consisting of refractive index …
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Explorations of DNA-Single-Walled Carbon Nanotube Interactions to Develop Multiplexed Molecularly Specific Biosensors for Inflammation
… of single-walled carbon nanotube (SWCNT) optical nanosensors capable of real-time, multiplexed, and molecularly specific cytokine detection through innovative use of single-stranded DNA (ssDNA) interfaces.</p> <p>First, an IL-6-specific DNA aptamer was employed as both a dispersing agent and …
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Label-free carbon nanotube sensors for glycan and protein detection
… second chapter we model the use of quantitative nanosensors in a weak affinity dynamic microarray (WADM) to simulate practical uses of these sensors in bioprocessing and clinical diagnostics. There is significant interest in developing new detection platforms for characterizing glycosylated …
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Interfacing living plants with nanomaterials for in planta sensing and plant biotechnology applications
… to deliver biomolecular cargo, as well as nanosensors to translate the invisible plant internal signaling into an optical readout easily interpreted by portable electronics.
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Intentional nonlinearity in the design of dynamic micro/nanomechanical resonators via nanomaterial-integrated fabrication
… fundamental and applied science. For example, nanosensors can be designed to sense physical quantities at the smallest scale, e.g., masses in atomic scale and forces as small as spin or hydrogen bonds; micro/nanoelectromechanical system (M/NEMS) based RF devices reach extremely high frequencies …
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Cyborg botany : augmented plants as sensors, displays and actuators
… plant's own signals. Next, lead (II) detection nanosensors are presented which reside inside the leaf of a plant and continuously sample through plant hydraulics. This is followed with a design study for plants with new conductive channels grown inside them and their subsequent use as …
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Electrically Conductive Low Dimensional Nanostructures: Synthesis, Characterisation and Application
… suitable for applications in nanodevices and nanosensors. In this work was developed a simple method to control the conformation and orientation of single adsorbed polyelectrolyte molecules by co-deposition with octylamine. A simple chemical route to conductive polypyrrole nanowires by the …
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Synthesis and characterization of novel boron-based nanostructures and composites
… a number of novel electronic nanodevices and nanosensors. A method to create nanocomposites by the chemical vapor infiltration (CVI) of nanomaterials into a metal matrix has been developed further. This work builds on past efforts which successfully developed carbon nanotube (CNT)-infiltrated …
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Ionic Liquids and GUMBOS for Biomedical and Sensing Applications
… ionic liquid based pH sensitive colorimetric nanosensors based on phosphonium and fluorescein. The pH dependent size changes in the nanodroplets are demonstrated and potential applications in detecting acidic environment and anticancer activity are investigated.
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