Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Nanosensor"”.
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An Optical Aptamer-Based Carbon Nanosensor for Cortisol Detection
… development of an optical aptamer-based carbon nanosensor for the detection of cortisol. The sensor utilizes single-walled carbon nanotubes (SWCNTs) functionalized with a specific DNA aptamer to achieve high specificity and sensitivity. This work touches on the importance of solvent selection in …
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Optimization of Optical Nanosensor Response for the Detection of Anthracyclines Using a Binary Machine Learning Classifier
… analyzing patterns in responses of fluorescent nanosensors to a class of chemotherapeutics and therefore detecting the specific anthracycline. We anticipate future work in developing multi-purpose nanosensors that monitor the pharmacokinetics of active pharmaceutics to decrease toxicity while …
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Construction and Performance Optimization of Bioconjugated Nanosensors for Early Detection of Breast Cancer and Pro-inflammatory Diseases
<p>In recent years, nanosensors have emerged as a tool with strong potential in medical diagnostics. Single-walled carbon nanotube (SWCNT) based optical nanosensors have notably garnered interest due to the unique characteristics of their near-infrared fluorescence emission, including tissue …
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MMP-7 nanosensors for urine-based detection of chemotherapy-induced senescence and pulmonary fibrosis
… protease was then utilised to develop an ALBANC nanosensor (Figure 1), comprising human serum albumin covalently linked to 1.6-nm gold nanoclusters (AuNCs) by MMP-7-cleavable peptides (Chapter 5). When injected intravenously, the nanosensor is cleaved by MMP-7 in senescence-enriched tissues or …
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Assessment of ion-selective optical nanosensors for drug screening applications
… An ion-channel assay system using optical nanosensors has recently been developed. This high-throughput, high-content system improves on the existing patch clamp and fluorescent dye technologies that presently dominate the ion-channel screening market. This paper introduces the nanosensor …
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Explorations of DNA-Single-Walled Carbon Nanotube Interactions to Develop Multiplexed Molecularly Specific Biosensors for Inflammation
… of single-walled carbon nanotube (SWCNT) optical nanosensors capable of real-time, multiplexed, and molecularly specific cytokine detection through innovative use of single-stranded DNA (ssDNA) interfaces.</p> <p>First, an IL-6-specific DNA aptamer was employed as both a dispersing agent and …
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Paper-based microfluidic device with a gold nanoparticle sensor for arsenic detection applied to groundwater in Bangladesh
… microfluidic device (μPAD) with a gold nanosensor (Au-TA-TG) to detect arsenic contamination in Bangladesh groundwater at the World Health Organization (WHO) guideline level (10 μg/L). A method has also been developed to prevent interference from alkaline metals (Ca, Mg, K and Na) by …
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Carbon nanotube-based optical sensors for pharmaceutical applications : theory and experiment
… described in this thesis spans several levels of nanosensor development including: i) the fundamental study of SWCNT-polymer interactions and their dependence on solution properties; ii) sensor development using existing detection modalities and the use of mathematical modeling to guide sensor …
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Estudio de dispositivos magnetométricos : aplicación al Proyecto NANOSAT
… Sistema de Control de Actitud del satélite y un nanosensor magnético basado en el Efecto Faraday de un material nanoestructurado como experimento.
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Bioanalytical methods for studies of homocysteine and novel cardiovascular disease indicators
… sensing scheme for protein homocystamide. The nanosensor provides visual conformation of protein homocystamide (N-Hcy-protein) by way of a red-to-blue color change. Further sensor investigations conducted with protein nanobioconjugates revealed that the GNP sensing mechanism is dependent on …
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Development of Low-power Wireless Sensor Nodes based on Assembled Nanowire Devices
… sensor node development: (1) post-IC assembly of nanosensor devices onto prefabricated complementary-metal-oxide-semiconductor (CMOS) integrated circuits using a technique called dielectrophoretic (DEP) assembly; and (2) design of a low-power SiGe BiCMOS multi-band ultra-wideband (UWB) transmitter …
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Micro and nanotechnology for cancer treatment
… We measure the presence of the drug nanosensor based on the change in T2 relaxation time using a miniaturized, handheld NMR sensor for point-of-care diagnosis. In the final section, we detail a photocleavable DNA barcoding method for understanding treatment response via multiplexed …
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Upconversion Nanoparticles for pH Sensing and Imaging
… this knowledge to the creation of a novel pH nanosensor for cellular imaging. High-temperature coprecipitation was used to synthesize b-phase UCNPs with shell layers of different thicknesses ($\leq$1 nm and 3 nm) to decrease surface quenching. The two types of particles were modified with …
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Protease activated nanosensors for the noninvasive diagnosis of community-acquired pneumonia
… pneumonia. We then used our lab’s activity-based nanosensor (ABN) technology to create a 20-plex panel of nanoparticles that could produce urinary signatures of disease state in response to the activity of a subset of these proteases. We validated that this panel could generate unique urinary …
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Functional gel for directed molecular transport and sensor applications
… gels and their integration with nanosensors. After the introduction in chapter 1, chapter 2 focuses on the effect of the chemical gradient miniaturization on the analyte collection capability and the spatial control of such gradient. Electrohydrodynamic printing, an ink-jet …
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Quantum dot - molecularly imprinted polymer nanomaterials for the fluorescence sensing of selected pharmaceutical and personal care products
… the QDs which provided a fluorescence “turn-on” nanosensor for the sensing of triclosan. The Förster distance in the system of GSH-CdSe/ZnS QDs-TCS was found to be approximately 4.0 nm which meets the distance required (<10 nm) for FRET to occur. The developed QDs were found to be a sensitive …
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Integrated nanoscaled detectors of biochemical species
Rapid and reliable diagnostics of a disease represents one of the main focuses of today’s academic and industrial research in the development of new sensor prototypes and improvement of existing technologies. With respect to demographic changes and inhomogeneous distribution of the clinical …
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Molecular Sensors at the Nanoscale: Modeling and Technology
L'abstract è presente nell'allegato / the abstract is in the attachment