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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 130 for “"Nanopores"”.
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Transport properties of synthetic nanopores
… with subnanometer precision, so-called synthetic nanopores. Immersed in aqueous solution, these nanopores can be deployed to study the translocation of charged molecules and ions, a process of main importance in biology. However, researchers run into problems to build and control such small …
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Genomics and epigenomics using 2D nanopores
… methylated DNA-MBD1 complex through 2D material nanopores under external voltage biases. The passage of the MBD1-labeled methylation site through the pore is identified by dips in the current blockage induced by the DNA strand, as well as by peaks in the transverse electronic sheet current across …
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Evaporation from nanopores : probing interfacial transport
… membrane (~200 nm thick) containing an array of nanopores (pore diameter ~100 nm). A gold layer deposited on the membrane served as an electric heater to induce evaporation as well as a resistive temperature detector to closely monitor the interface temperature. This configuration minimizes the …
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Nanopores for detecting and sensing biological molecules
… proteins, aminoacids, etc.) with solid-state nanopores, atomically-resolved scanning and detection of these molecules remains a significant challenge. In most nanopore-based DNA sequencing and single molecule detection techniques, ionic current blockade and blockade duration are the primary …
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DNA translocation through an array of kinked nanopores
Synthetic solid-state nanopores are being intensively investigated as single-molecule sensors for detection and characterization of DNA, RNA, and proteins. This field has been inspired by the exquisite selectivity and flux demonstrated by natural biological channels and the dream of emulating these …
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Molecular Sensing with Protein and Solid-State Nanopores
… the techniques for producing solid-state nanopores in thin membranes of silicon nitride and how these nanopores can be integrated into a fully functioning nanopore sensor system. I will then explore two applications of this system. First, a study of adsorption of bovine serum albumin …
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Graphene supported hafnium oxide nanopores for DNA sensing
… technologies. In particular, solid-state nanopores are investigated and recent developments in the field are discussed. The interdisciplinary effort from researchers to establish solid-state nanopores as a viable sequencing platform is thriving on multiple fronts including surface charge …
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Design and fabrication of asymmetric nanopores using pulsed PECVD
… and biological applications. Structures such as nanopores demonstrate a phenomenon known as hindered transport which can be exploited in analytical applications such as DNA sequencing, ionic transistors, and molecular sieving. Precisely controlling the size, geometry and surface characteristics …
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Computational optimisation strategies for targeted DNA sequencing using nanopores
… behind this transformation is sequencing using nanopores that act as biosensors measuring fluctuations of an ionic current caused by traversing polynucleotides. By partially blocking the flow of ions, distinct patterns of current are generated as nucleotides pass through the narrowest …
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Desalination of water by vapor transport through hydrophobic nanopores
… by vapor-phase transport through hydrophobic nanopores in an isothermal condition. Hydrophobic nanopores flanked by vapor-interfaces with a submicron gap provide a complete barrier for salt while behaving as highly permeable medium for water. We first theoretically explore transport of water …
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MOLECULAR ANALYSIS OF HYALURONIC ACID (HA) USING SOLID-STATE NANOPORES
Hyaluronic acid (HA; hyaluronan) has emerged as a powerful indicator for a range of diseases and physiological conditions, including cancer, osteoarthritis, and wound healing after injury. Evidence has shown that low molecular weight HA is pro-inflammatory while high molecular weight HA is …
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Detection of Nucleic Acid Disease Biomarkers Using Solid-State Nanopores
… achieved. While this device utilizes biological nanopores, Solid-State Nanopore sensors were also initially investigated to develop sequencing devices. Significant efforts are being made to this day towards this end, with advances and improvements being made to amplifiers and using various 2-D …
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Molecular transport in nanopores with fluctuations, deformation, and potential leakage
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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Macroscopic graphene membranes with tunable nanopores for highly selective mass separation
… is carried out to introduce a high density of nanopores in large-area graphene membranes. Pore creation parameters are thoroughly explored to investigate the influence on pore size and density. The resulting transport properties of graphene membranes can be tuned to achieve high permeance to …
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Growth of anodic alumina nanopores and titania nanotubes and their applications
Anodic aluminum oxide (AAO) nanopores are excellent templates to fabricate different nanostructures. However, the pores are limited to a hexagonal arrangement with a domain size of a few micrometers. In this dissertation, focused ion beam (FIB) is used to create pre-patterned concaves to guide the …
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Detecting DNA Using Silicon Nanopores and 20--40 Nm Gate-Length RFNMOSFET
Lastly, we describe using a nanopore in a MOS-capacitor membrane to sense the charge in DNA. As DNA translocates the nanopore, the electrostatic charge distribution should polarize the capacitor and induce a voltage on the electrodes, which will be measured by our nanotransistors implemented right …
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Structure, property and transport mechanism of water and electrolytes in graphene nanopores
… Owing to its ultrathin thickness, graphene nanopores are promising candidates for various applications such as water desalination, single molecule sensing, etc. Understanding water and ion transport mechanisms and properties in membranes is essential to characterize and design membranes for …
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Ion transport in multilayer solid-state nanopores for memory and biosensing applications
Solid-state nanopores have emerged as powerful platforms for investigating nanoscale transport phenomena and single-molecule sensing, owing to their structural robustness, chemical stability, and ability to simultaneously probe ionic and in-plane currents during biomolecule translocation. This …
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Characterization of nanopores with internal cavities for DNA manipulation using Langevin dynamics simulations
A novel nanopore geometry is proposed, in which a larger internal cavity is located inside a traditional nanopore. Polymer translocation through this geometry is studied using coarse-grained Langevin dynamics. The most striking result is that translocation time through the system is found to be …
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Molecule transport in nanopores with applications to water purification, power generation and disease diagnosis
High performance water transport in nanopores has drawn a great deal of attention in a variety of applications, such as water desalination, power generation and biosensing. A single-layer MoS2 nanopore is shown, here, to possess high water transport rate and strong salt rejection rate making it …
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