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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 28 for “"Nanoparticle tracking analysis"”.

  1. Elucidating the Relation between Human Milk Fatty Acids, Extracellular Vesicles, and Infant Developmental Outcomes in the First Year of Life

    Bickmore, Diana2020

    … in diet. Extracellular vesicles (EVs) are nanoparticles containing a lipid bilayer membrane and are present in human milk. Methods of EV isolation such as ultracentrifugation (UC) may not be feasible for the study of EVs in human milk due to the need for large sample volume, which may not …

    chapman Repository record

  2. Design, Synthesis, and Characterization of Magnetite Clusters using a Multi Inlet Vortex Mixer

    Mejia-Ariza, RaquelVirginia Tech2010

    Superparamagnetic nanoparticles have potential applications in targeted drug delivery and as magnetic resonance imaging contrast agents. Magnetite clusters are of particular interest for these applications because they provide higher magnetic flux (under a magnetic field) than individual magnetite …

    vt Repository record

  3. The precipitation of candidate drugs on mixing DMSO stock solutions with aqueous buffers

    Gillespie, CheskaUniversity of Strathclyde2013

    … growth of these particles can be monitored using nanoparticle tracking analysis (NTA) and the NanoSight. We show that the presence of these particles can interfere with the results of 'kinetic solubility' measurements, depending on the exact analysis used. It is already known that these types of …

    strathclyde Repository record

  4. High Frequency Irreversible Electroporation (H-FIRE) as a Therapeutic Modality for Liver Cancer Treatment and Its Effect on the systemic Extracellular Vesicle Population

    Tellez Silva, AlejandraVirginia Tech2024

    … plasma via filtration and ultracentrifugation. Nanoparticle Tracking Analysis (NTA) quantified EV concentration and size distribution. Ten patients provided pre- and post-treatment plasma samples. The median EV concentration in peripheral blood increased from 2.56 x 10^11 particles/ml …

    vt Repository record

  5. Comprehensive Proteomic Analysis and Characterization of Human Bone Marrow Mesenchymal Stem/Stromal Derived Extracellular Vesicles

    Munshi, Afnan M N AlamUniversité d'Ottawa / University of Ottawa2019

    … of hBM-MSC-EVs using a quantitative proteomics analysis. hBMMSC-EVs were produced from 5 hBM-MSC donors characterized by Nanoparticle Tracking Analysis showed no differences in the hBM-MSC-EV concentration and size among the 5 donors (1.83 x 10¹⁰ ± 3.23 x 10⁹ /mL), with the mode particle size …

    ottawa-retro Repository record

  6. Evaluation of small extracellular vesicular microRNAs as biomarkersfor exposure of nicotine and E-liquids on human lung cells

    Chinta, S2022

    … Characterization of sEVs was performed using nanoparticle tracking analysis (NTA), fluorescent NTA (fNTA) and western blot. MiRNA expression profile for miRNAs from C14MC was measured by qPCR using the 2^ΔΔCt method. Massively parallel sequencing of small RNA was performed to identify sEV …

    salford Repository record

  7. HOW MICROVESICLES ARE "BUDDING" INTO THE CANCER CONVERSATION: THE ROLE OF GLYCOCALYX-INDUCED MEMBRANE BENDING

    Roberts, LaDeidra MonetCornell University2019

    … microscopy for visualization of EVs along with nanoparticle tracking analysis for diameter distributions and quantification. We found these methods to be reliable in characterizing and differentiating EV subtypes. We then used these techniques along with our genetically encoded toolbox of …

    cornell Repository record

  8. Inhibition of extracellular vesicle release enhances cancer chemotherapy and inhibition of outer membrane vesicle release sensitises bacteria to antibiotic and bacteriophage therapy

    Kosgodage, Uchini S.London Metropolitan University2019

    … MCF7, breast cancer cells. Flow cytometry (FCM), nanoparticle tracking analysis (NTA) and fluorescent microscopy were used for the investigation. All inhibitors tested were shown to inhibit EV release with minimal effect on the cell viability. Peptidyl Arginine Deiminase (PAD) inhibitor, …

    london-metro Repository record

  9. Obesity and neuroinflammation : the impact of adipocyte-derived extracellular vesicles on microglial cell signalling

    Colvin, ChiaraUniversity of Strathclyde2022

    … understood. Extracellular vesicles (EVs) are nanoparticles released from most cell types and aid in cell-cell communication. Adipocyte-derived extracellular vesicles (AT-EVs) are known to be involved in interorgan crosstalk during obesity and therefore may be a key component in obesity induced …

    strathclyde Repository record

  10. Caractérisation morphologique et moléculaire des vésicules extracellulaires libérées par des cellules musculaires primaires humaines provenant d'individus sains et les personnes atteintes de diabète de type 2

    Yapi, AssiUniversité d'Ottawa | University of Ottawa2025

    … différenciées et caractérisées par analyse NTA (Nanoparticle Tracking Analysis), par dosage des protéines totales, et par Western blot pour les marqueurs vésiculaires TSG101, CD63, CD81. Parmi les méthodes d’isolement testées, ExoQuick et EasySep se sont révélés être plus performants en termes de …

    ottawa-retro Repository record

  11. Microrna 21 targets B Cell Lymphoma 2 (Bcl2) Mrna to increase beta cell apoptosis and exosomal Microrna 21 could serve as a biomarker of developing Type 1 Diabetes Mellitus

    Sims, Emily K.2018

    … and increased cleaved caspase 3 production. Analysis of EVs from human beta cells and islets exposed to cytokines revealed a 3-5-fold increase in miR-21. Nanoparticle tracking analysis showed no changes in EV quantity in response to cytokines, implicating specific changes within EV cargo as …

    iupui Repository record

  12. Epigenetic influence on cardiovascular protective mechanisms in vivo: explorations of t-PA release and extracellular vesicle genetic content

    Tempelman Svennerholm, Kristina2015

    … by western blot, electron microscopy and nanoparticle tracking analysis. Changes in EV genetic content after IPC were identified by microarray and DNA sequencing. Results: Animals treated with VPA demonstrated a significantly higher cumulative transcoronary t-PA release compared to …

    goteborg Repository record

  13. The cellular and molecular origins of extracellular vesicles secreted by <i>Fasciola hepatica</i>

    Bennett, AdamQueen's University Belfast2019

    … their cellular origins in adult flukes. This analysis revealed multiple sites of FhEV production (the parenchyma, tegument, gastrodermal cells and protonephridial system) and indicated that further subtypes of FhEVs exist within the previously characterised 15K and 120K EV populations. …

    qu-belfast Repository record

  14. Development of a multi-stage purification process for serum-derived exosomes and evaluation of their regenerative capacity

    de Boer, CandiceDepartment of Surgery2020

    … applications and analyses such as proteomic analysis, a multistep purification method was developed. A simple 3-step density gradient (DG) UC was introduced prior to SEC that incorporated a high-density iodixanol cushion overlaid by a 18% iodixanol step containing UC concentrated human serum …

    cape-town Repository record

  15. From Spheres to Sheets: Colloidal Hydrodynamics, Thermodynamics, and Statistical Inference

    Silmore, Kevin StantonMassachusetts Institute of Technology2021

    … method that we call Maximum A posteriori Nanoparticle Tracking Analysis (MApNTA) for estimating the size distributions of nanoparticle samples from high-throughput single-particle tracking experiments. We show that this approach infers nanoparticle size distributions with high resolution …

    mit Repository record

  16. Dysregulation of connexin-43 (cx43) in doxorubicin-induced cardiotoxicity

    Veerman, Ben E. P.University of Strathclyde2024

    … upon direct drug effects on cardiac function. Nanoparticle tracking analysis of DOX-treated MDA-MB-231 cells did indeed result in significantly increased EVs released with no change in particle size (120-250nm). Challenges were experienced when investigating the exosomal Cx43 during DOX …

    strathclyde Repository record

  17. Vesículas extracelulares de microorganismos enológicos

    Mejías Ortiz, MiguelUniversidad de La Rioja (España)2026

    … ultracentrifugación. Se caracterizaron mediante nanoparticle tracking analysis (NTA) y se estudió su contenido proteico. Se ha observado que O. oeni produce vesículas extracelulares con un proteoma enriquecido en proteínas ribosomales, proteínas integrales de membrana y enzima maloláctica, lo que …

    dialnet Repository record

  18. Uptake of Small EVs by Skeletal Muscle Myoblasts In Vitro and Subsequent Myogenic Response to Cargo

    Dlamini, NonhleStellenbosch : Stellenbosch University2026

    … isolated using differential ultracentrifugation. Nanoparticle tracking analysis confirmed that the majority of isolated particles were within the expected size range (mean diameters below 200 nm). Cell Mask Orange staining demonstrated that 74.45% of the isolated particles were membrane-bound and …

    stellenbosch Repository record

  19. The Change in the Concentration Levels of Extracellular Vesicles and of Cytokines in the circulatory blood system in Response to different exercise protocols

    Abu-Seer, Ayman AOxford Brookes University2021

    … subjects. EVs were prepared and isolated, and Nanoparticle Tracking Analysis (NTA) was then used to assess EV concentration levels and vesicle sizes. A mouse muscle cell line (C2C12) model was used to explore the effect of exercise on EVs concentration levels. As a measure of changes in …

    oxford-brookes Repository record

  20. The use of nanotechnology in enhancing the efficacy of cosmetic actives of natural origin

    Moddaresi, Mojgan2019

    … by photon correlation spectroscopy (PCS) and by nanoparticle tracking analysis method (NTA). The TA-LNC have proven to be monodisperse, with the particle size of less than 60 nm and stable for at least 28 days in different temperatures (0 °C, 4°C and 28°C). The nanocarriers showed 57.7 ± 4.9% …

    arts-london Repository record

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