Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Nanoparticle Aggregation"”.
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Incorporating Magnetic Nanoparticle Aggregation Effects into Heat Generation and Temperature Profiles for Magnetic Hyperthermia Cancer Treatments
… to the dose that healthy tissue receives. Nanoparticle (NP) based treatments offer many advantages for target specificity compared to other forms of treatment due to their ability to selectively target tumors. One benefit of using magnetic NPs is their ability to release heat, which can …
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Single-Molecule and Ensemble Measurements Inform on the Role of Protein Crowding at Interfaces
… relevant quantities of serum albumin stabilize nanoparticles in solution, while decreased protein concentrations induce nanoparticle aggregation. The first aim of this dissertation was to characterize the crowding mechanism of the most abundant serum protein, serum albumin. Many studies have …
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Numerical Study of Acoustophoretic and Thermophoretic Aggregation of Micro- and Nano-Sized Particles
Precise manipulation of bio-micro/nanoparticles, including cells, platelets, bacteria, and extracellular vesicles, is critical for tumour diagnostics, infectious disease detection, and cell analysis. The acoustofluidic aggregation method shows its significant advantages in microparticle …
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Controlled Evaluation of Silver Nanoparticle Dissolution Using Atomic Force Microscopy
Incorporation of silver nanoparticles (AgNPs) into an increasing number of consumer products has led to concern over the potential ecological impacts of their unintended release to the environment. Dissolution is an important environmental transformation that affects the form and concentration of …
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Responsive, multimodal imaging agents for MRI: advancing the detection of metals and oxidized species implicated in neurodegenerative disorders
… starting with the nature of the iron oxide nanoparticles. Thee relaxivity of the nanoparticles was found to be dependent on the total anisotropy of the particles themselves, which is in turn a function of the size, shape, composition, surface coating, and interparticle distance of the …
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Variance Spectroscopy and its Application to the Study of Single-Wall Carbon Nanotubes
… variations in the local composition of dilute nanoparticle samples. The data are spectrally resolved, allowing for the analysis of individual SWCNT emitters in a complex sample. Several thousand statistically independent spectra from different regions are measured using custom instrumentation. …
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SERS-based nanoparticle biodetection using carbohydrate-lectin interactions
… glycobiological interactions using sugar-coated nanoparticles are the basis for the research described herein.Metallic nanoparticles were coated with a variety of thiol-based linker molecules. Heterobifunctional PEG (carboxyl/thiol) molecules were found to be most successful in preventing …
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A photonic crystal biosensor application for assessment of iron deficiency
… worldwide. A novel application using iron-oxide nanoparticles (IONs) and a photonic crystal (PC) optical biosensor as an immunodiagnostic platform for detection of serum ferritin and soluble transferrin receptor (sTfR), biomarkers for iron deficiency, is presented. Two assay formats were explored …
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Dye sensitized solar cells: optimization of Grätzel solar cells towards plasmonic enhanced photovoltaics
… Recently, the incorporation of metallic nanoparticles into silicon solar cells has shown improved efficiency and lowered material cost. By utilizing their plasmonic properties, incident light can be scattered, concentrated, or trapped thereby increasing the effective path length of the …
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Interaction of azobenzene containing surfactants with plasmonic nanoparticles
… I investigate the complexes between noble metal nanoparticles and cationic surfactants containing azobenzene units in their hydrophobic tail, employing absorption spectroscopy, surface zeta-potential, and electron microscopy. In the first part of the thesis, the formation of complexes between …
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Nanoemulsion-Loaded Hydrogels For Advanced Pharmaceutical Formulations
… the nanoemulsion into various dosage forms (nanoparticle suspension, drug tablet, and oral thin film) in a manner that avoids nanomilling. Finally, we develop thermogelling hydroxypropyl methylcellulose (HPMC) nanoemulsions as robust templates to formulate oral films loaded with poorly …
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Controlled Evaluation of Silver Nanoparticle Dissolution: Surface Coating, Size and Temperature Effects
… and evaluated in many published studies. Silver nanoparticles (AgNPs) represent one of the most widely manufactured nanomaterials. They are currently being incorporated into a wide range of consumer products due to their purported antimicrobial properties. However, either the AgNPs themselves or …
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Mechanisms of polymer adsorption in nanoparticle stabilization for poorly water soluble compounds
… stabilization via polymer adsorption on nanoparticle surface were investigated. As the electrokinetic behavior and colloidal stability depend on the surface characteristics, altering the surface adsorbed polymers affords the different surface properties of nanoparticles and leads to the …
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Hierarchical protein assemblies with biomedical applications
… that has garnered interest is using inorganic nanoparticles as antimicrobial agents. While these nanoparticles can often overcome traditional drug resistance by targeting multiple areas of the cell, their usage in medical applications is limited due to their lack of biocompatibility. The first …
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High-resolution direct ink writing of soft conductive materials
… limitations. The most vital limitation is nanoparticle aggregation at printing tips, which significantly hampered high-resolution printing (<100 μm). High-resolution 3D printing of conductive polymers offers the possibility to discriminate a single cell’s behavior rather than signals from …
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Nanostructured Devices for Ultrasensitive and High Throughput Vibrational Spectroscopic Imaging
An outstanding challenge in biomedical sciences is to devise systems that can enable rapid, simultaneous and quantitative imaging of tens to hundreds of species at ultra-low concentrations. Central to addressing this challenge is the availability of a modality capable of sensitive, rapid, …