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Showing 1 to 4 of 4 for “"Nanonet"”.
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Investigating Cell Viscoelastic Properties with Nanonet Force Microscopy
… fiber manufacturing platform, we developed fused nanonets to measure single-cell forces and viscoelasticity. Using computer-controlled probes, we stretched single cells attached to two-fiber and three-fiber systems precisely and recorded the relaxation response of cells. The viscoelastic …
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Cell-Fiber Interactions: A New Route to Mechano-Biological Investigations in Developmental and Disease Biology
… of a first-of-its-kind force measurement 'nanonet' platform capable of investigating cell adhesion forces in response to symmetric and non-symmetric (injury model) loading. Our combined findings are multi-fold: (i) Cells on suspended fibers are able to form focal adhesion clusters …
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Single Cell Force Platforms to Link Force-ECM Coupling in Pathophysiology
… the force feed-forward loop impacts cell fate. Nanonet Force Microscopy (NFM) comprised of aligned nanonets is designed to study anisotropic cell shapes, while Crosshatch Force Microscopy (CM) comprised of orthogonal arrangement of fibers is designed to study cell bodies of broad shapes. The …
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Investigation of Single-Cell and Blood-Brain Barrier Mechanics after Electroporation and in Primary Brain Cancers
… cells after reversible electroporation using Nanonet Force Microscopy (NFM). A precise network of extracellular-matrix mimicking nanofibers enabled cell attachment and contraction, resulting in measurable fiber deflections. Cell contractile forces were shown to be temporarily disrupted after …