Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Nanogels"”.
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Synthesis and comprehensive studies of nanogels for enhanced oil recovery
… nano-sized crosslinked polymeric gel particles (nanogels) have shown the potential in improving both the macro- and micro-displacing efficiency. This dissertation focuses on the synthesis and the potential EOR mechanisms of nanogels. Nanogels with positive, negative, and neutral charges were …
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Development of nanogels from nanoemulsions and investigation of their rheology and stability
… and long-term stability of viscoelastic nanogels developed from liquid nanoemulsions. At first, gelation in 40 wt% canola oil-in-water nanoemulsions were investigated as a function of emulsifier type (anionic sodium dodecyl sulfate (SDS) or nonionic Tween 20) and concentration. Three …
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Biodegradable dextran and PEG micro- and nanogels: physicochemical properties and sustained drug delivery features
De laatste jaren is de ontwikkeling van macromoleculaire geneesmiddelen in de strijd tegen erfelijke ziekten, kanker of hart- en vaatziekten enorm toegenomen. Het potentieel van deze peptiden, eiwitten of (oligo)nucleotiden zou haast oneindig zijn, ware het niet dat er zich nog verschillende …
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Engineering of poly(2-oxazoline)s for a potential use in biomedical applications
… design of poly(2-oxazoline) (POx) hydrogels and nanogels, by chemical or physical cross-linking, aimed to be used for biomedical applications. Nanogels were first prepared in dilute media and in inverse emulsion based on a statistical copolymer made of 2-ethyl-2-oxazoline and ethylene imine …
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The design of multifunctional hydrogel nanoparticles for drug delivery
Hydrogel micro- and nanoparticles (microgels and nanogels) are a promising class of drug delivery vehicles. Composed of hydrophilic polymers arranged into a cross-linked network structure, nanogels show several attractive features for the delivery of macromolecule therapeutics. For instance, the …
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Design of injectable hydrogels and nanogels relying on Schiff-base crosslinking of custom-made poly(ether urethane)s and photo-cured methacryloyl gelatin for in situ drug delivery and biological tissue mimics
L'abstract è presente nell'allegato / the abstract is in the attachment
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Stimuli-Responsive Polymer Systems that Respond to Redox Potential and pH for Controlled Drug Release
… are composed entirely of disulfide bonds, these nanogels specifically degrade to small molecule dithiols intracellularly in response to the reducing agent glutathione present inside of cells. Due to the ease of synthesis, rapid gelation times, and tunable functionality, these non-toxic and fully …
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Endogenous and exogenous control of polymers for spatiotemporally defined drug delivery
… temporarily stable nanodroplets and stable nanogels. Second, two acid-labile biodegradable liquid polymers were investigated for pH-responsive intracellular delivery of the immunomodulator R848 (or Resiquimod), a poorly soluble adjuvant for a melanoma vaccine. Third, nanodroplets of one of …
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Surfactants in nonpolar oils: agents of electric charging and nanogel templates
… and templates for the synthesis of novel nanogels with promise for drug delivery. Synthesis via copper-free Click chemistry is shown to allow for better control of the particle size than a more conventional polymerization scheme, while avoiding metal catalysts and free radicals that are …
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Development and biophysical characterization of a hyaluronic acid – vitamin E conjugate as a subcutaneous delivery platform
… while sustaining their therapeutic efficacy. Nanogels, formed from amphiphilic polymers, combine the unique and tunable properties of hydrogels and nanoparticles into one drug delivery system and have the potential to drastically improve the clinical applicability of protein therapeutics …
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Janus Particles at Interfaces
… thermo-responsive inorganic/organic hybrid nanogels with an intermediate protective silica shell and an interactive polymer layer. These well-defined multifunctional nanogels were prepared via two consecutive encapsulation processes of superparamagnetic and/or fluorescent semiconductor …
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Biodegradable Polymeric Biomaterials in Different Forms for Long-acting Contraception and Drug Delivery to the Eye and Brain
… oly(N-isopropylacrylamide-co-Dextran-lactateHEMA) nanogels for the potential delivery of hydrophilic peptide (insulin) across ocular barriers for the treatment of diabetic retinopathy. The in vitro, and ex vivo studies showed that the developed nontoxic nanogels have great potential to enhance the …
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Intelligent Nano/Microgels for Cell Scaffold and Drug Delivery System
… magnetic Fe3O4 nanoparticles enable such hybrid nanogels to delivery pharmaceuticals to a specific site of the body by applying a gradient magnetic field. </p> <p>Chapter 6 investigated a class of well-defined glucose-sensitive microgels as an insulin drug release carrier, obtained via …
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Investigations of biphasic seeded emulsion polymerizations in a continuous tubular reactor
… 7 will cover investigations into the use of two nanogels as seeds for the emulsion polymerization of MMA. This chapter describes several investigations, first to determine the nanogel latex’s stability at a range of pHs, temperatures and initiator loadings; second, nanogel ability to polymerize; …
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Arming adoptively transferred T-cells with drug-loaded nanoparticles for cancer immunotherapy
… nanoparticles. Anti-CD45 decorated nanogels consisting of IL-15 superagonists remained on T-cells surfaces for over 12 days and induced 15-fold T-cell expansion in tumors in vivo and significant tumor regression without toxicity, while equivalent doses of free IL-15Sa were lethal. …
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Microfluidic formation of hierarchical micro and nano emulsions for biomedical applications
… these nanoemulsions acted as templates to form nanogels, which had the ability to permeate through mammalian cancer cell membranes and deliver intracellular cargo. Finally, in order to gain a better understanding of the processes involved in protein self-assembly, novel label-free approaches …
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Application of chitosan-carbon nanotube hydrogel beads composite in the removal of antibiotic compounds and perfluoroalkyl substances from aqueous solution
This thesis is submitted for the fulfilment of academic requirements for the degree of Doctor of Engineering: Chemical Engineering, Durban University of Technology, Durban, South Africa, 2025.