Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Nanodroplets"”.
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Ultrasound Drug Delivery through Functionalized Nanodroplets and Nanoparticles
L'abstract è presente nell'allegato / the abstract is in the attachment
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Imaging the shapes and dynamics of superfluid helium nanodroplets
… nanoparticles or, more precisely, helium nanodroplets, via scattering of extreme-ultraviolet light pulses. In particular, the recent development of free-electron lasers (FELs) delivering intense short-wavelength light pulses of femtosecond duration is a promising prospect for the study of …
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Laser-activated perfluorocarbon nanodroplets as a tool in neurological applications
Perfluorocarbon nanodroplets (PFCnDs) are an emerging class of nanoagents for biomedical applications. These nanoparticles are unique in their ability to phase change from liquid nanodroplet to gas microbubble when activated by electromagnetic energy. The ability of PFCnDs to phase change when …
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Nucleation mechanism of crystal formation during antisolvent or cooling induced crystallisation
… composied of sub-micron valine-rich liquid nanodroplets with an average size and size distribution depending on supersaturation and the mixing conditions used during sample preparation. The supersaturated solutions prepared by cooling crystallisation, without agitation produced smaller …
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Endogenous and exogenous control of polymers for spatiotemporally defined drug delivery
… implantable matrix, temporarily stable nanodroplets and stable nanogels. Second, two acid-labile biodegradable liquid polymers were investigated for pH-responsive intracellular delivery of the immunomodulator R848 (or Resiquimod), a poorly soluble adjuvant for a melanoma vaccine. Third, …
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The effect of interfacial compositions on the dispersed phase-induced gelation and controlled digestion of mono and bilayer nanoemulsions
… we related to strong repulsive forces between nanodroplets. To further increase the δ, a second layer of polysaccharide (chitosan and pectin) with different magnitude of charge was deposited on Citrem and whey protein isolate (WPI)-stabilized nanodroplets, respectively. Two different …
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On the Physics of Ice Nucleation and Growth in Nanoscale
… transfer. Water-ice transformation of few nm nanodroplets plays a critical role in nature including climate change, microphysics of clouds, survival mechanism of animals in cold environments, and a broad spectrum of technologies. In most of these scenarios, water-ice transformation occurs in a …
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Investigation of Histotripsy Cavitation and Acoustic Droplet Vaporization From Perfluorocarbon Nanoparticles
… of histotripsy. Prior studies have shown that nanodroplets (NDs) and nanocone clusters (NCCs) both reduce the cavitation threshold, but further investigation on different parameters to optimize treatments have not fully been studied. Additional research is needed for the characterization of …
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Nucleation and growth of pharmaceutical crystals
… show the formation, growth, and order of dense nanodroplets leading to crystallization of OZPN dihydrate on the surface of OZPN I. Dihydrate polymorphic form is driven by a templating effect of the underlying OZPN I lattice. The size and volume fraction of nanodroplets in purely aqueous and …
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Ionic Liquids and GUMBOS for Biomedical and Sensing Applications
… and nanoGUMBOS as well as ionic liquids and nanodroplets are explored as possible chemotherapeutic agents with minimal toxicity to normal cells. In the first part of my dissertation, exploitation of ionic liquid chemistry to modulate toxicity of rhodamine 6G is reported. Rhodamine 6G-based …
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Experimental and computational study of mass transport in novel emulsion systems : strategies for reaction engineering and microparticle preparation
… droplets, which are 10-100 pm in size, and nanodroplets, which are dispersed as a nano- or mini-emulsion. Chemically, thermally, or electrically induced coalescence and micelle activity control the mass exchange between micro- and nano-droplets, leading to applications in reaction …
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From Solution Into the Gas Phase: Studying Protein Hydrogen Exchange and Electrospray Ionization Using Molecular Dynamics Simulation
… MD approach to simulate protein-containing nanodroplets, finding that natively‑folded proteins remain solvated as droplets shrink. Residual charge carriers remain following desolvation, consistent with Dole’s charged residue model.
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Analyzing the interactions of thermoresponsive coacervate-forming biodegradable polyester encapsulation on model protein structure and activity
… phase separates from the aqueous phase to form nanodroplets within solution, capturing bioactive molecules. Limited research demonstrates if TR-PEs can encapsulate and preserve a larger protein’s activity and how these TR-PEs interact with a protein on the biophysical level. It was determined …
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Contact Angle Of A Nano-Drop On A Heterogeneous Surface
… perimeter region somewhat arbitrary. We simulate nanodroplets of water on graphene-like surfaces having hydrophobic and hydrophilic interaction energy at the perimeter and beneath the drop using molecular dynamics. The microscopic analogue of the contact angle was extracted from simulation …
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Nanoemulsion-Loaded Hydrogels For Advanced Pharmaceutical Formulations
… gelled network effectively immobilizes the oil nanodroplets for confined nanoparticle crystallization and avoids potential irreversible nanoparticle aggregation. The oral films possess a tunable immediate release, and a scaling rule is developed for designing the release profiles of oral films.
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Probing Nucleation Mechanisms of Gas Hydrates via Molecular Simulations
… nucleation mechanisms of gas hydrates in water nanodroplets with pure-guest and mixed-guest species reveals key factors affecting hydrate nucleation behavior, including guest species, guest compositions, size of the nanodroplet, and temperature. The effects of temperature and the size of the …
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Microfluidic synthesis and properties of bio-inspired colloids
… well with experimental data. Encapsulating nanodroplets in the hydrogel network allows us to generate and preserve small droplets under nearly surfactant-free conditions via quick washing steps post-synthesis.
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Development of nanogels from nanoemulsions and investigation of their rheology and stability
… rotational and translational diffusion of nanodroplets on the surface of each other leading to network compactness and a decrease in gel strength with time. Overall, it was concluded that it is possible to form nanogels from canola oil nanoemulsions using ionic emulsifiers. The gel strength …
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Molecular Dynamics Investigation of the Thermodynamics of Nanoscale Droplets and Kinetics of Weakly Correlated Systems
<p>The surface tension of nanoscale droplets of water was studied with molecular dynamics simulations using the BLYPSP-4F water potential. The internal pressure of the droplet was measured using a correlation between the pressure and density, established through a series of bulk simulations …