Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Nanochannel"”.
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Studies of DNA dynamics in slit-like nanochannel confinement
The ability to visually observe single DNA molecules has greatly improved our understanding of polymer physics, from gel electrophoresis to the theology of dilute (and even concentrated) polymer solutions. The use of DNA in these general studies, though, resulted in a depth of specific knowledge …
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Development of an electrostatic peristaltic gas micropump and nanochannel fabrication technique
… nanofluidics components including nanopores and nanochannels. A nanopore with an embedded electrode is fabricated on a 20 µm thick SU-8 layer by using a focused ion beam. The diameter of the nanopore is about 500 nm. 100 mM phosphate buffer is used as an electrolyte and transported by …
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Design and Fabrication of Nanofluidic Systems with Integrated Sensing Electrodes for Rapid Biomolecule Characterization
… with 15-45 micrometer separation gaps in the nanochannel region. Sensing electrodes (up to one micron wide) were then deposited using FIB to bridge the gaps. The nanochannels were realized through both AFM nanolithography and FIB milling techniques, which simultaneously cut through the …
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Nano-pipette as nanoparticle analyzer and capillary gated ion transistor
… provides control of ionic transport through nanochannel by gate voltage. CIT is Ionic transistor, which employs pulled capillary as nanochannel with a tip diameter smaller than 100 mm. We observed that the gate voltage applied to gate electrode, deposited on the outer wall of a capillary, …
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A study of conformational response of DNA to nanoconfinement by Monte Carlo simulation
… by a cylindrical potential, which mimics the nanochannel, alters certain structural properties of the supercoil. The simulation results were interpreted with the wormlike chain model. The simulation model was further employed to simulate a supercoil in a dense solution where the simulated form …
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Nonlinear electrokinetic transport and its applications under combined AC and DC fields in micro/nanofluidic interface devices
… for different nondimensional EDL thickness and nanochannel wall surface charge density. We understand that for a highly ion−selective nanochannel, the application of combined AC/DC electric field, at amplitudes greater than the DC voltage and at low Strouhal number, results in large dual …
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CMOS nanofluidics
… gate polysilicon as a sacrificial layer. A nanochannel with critical dimension of 100nm and length of 200 [mu]m is fabricated. Actuation and separation of bio-molecules in the nanochannel with electrophoresis is demonstrated. We then incorporate avalanche photodiodes (APD) in CMOS. …
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Polyelectrolyte multilayers (PEM) in micro / nanofluidics for novel BioMEMS platforms
… to the nanometer scale without channel collapse. Nanochannel-induced fluidic conduction can be enhanced by controlling the channel gap size for increasing electrical double layer (EDL) overlap as well as fabricating high-throughput vertical nanofluidic channels. We have fabricated a vertical …
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PROTON BEAM WRITING OF MICRO/NANO FLUIDIC DEVICES FOR DNA ANALYSIS AND PARTICLE SEPARATION
… used for the study of DNA configuration using a nanochannel confinement and particle separation using a ratchet structure. PBW is a direct write technique can be focused down to sub 30 nm size. Proton beam can penetrate a photoresist very deep with minimal proximity effects allow us to fabricate …
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Development of an Enzyme-Linked ImmunoSorbent Assay (ELISA) with Enhanced Sensitivity in a Nanofluidic System
… in nanofluidic channels. Binding events in the nanochannel were detected using electrical and fluorescence methods. We concluded that antibody-antigen binding constants in nanochannels were similar to experiments performed in microtiter plates at low antigen concentrations; however the bound …
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FABRICATION OF POLYMER NANOFLUIDIC CHIPS WITH PROTON BEAM WRITING AND NANOIMPRINTING FOR DNA LINEARIZATION
… Nanopatterning and fabrication methods for nanochannel devices are discussed with focusing on proton beam lithography, Ormostamp mold casting, nanoimprinting on PMMA and bonding procedures. Among various nanofabrication methods and chip substrate material, several type of polymer substrates …
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Experimentally validated 3D MD model for AFM-based tip-based nanomanufacturing
… conditions for guiding the fabrication of nanochannels (e.g. scratch rate = 0.996 Hz, trigger threshold = 1 V, for achieving a nanochannel depth = 50 nm for the case of gold device). Similar trends for the variation of indentation force with depth of cut, pattern of the material pile-up …
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Collocation Based Meshless Methods for Microelectromechanical Systems
… transfer between the microchannels through a nanochannel under rest, injection and recovery stages of operation by varying the applied potential bias. During the injection stage, the phenomenon of ion accumulation and depletion is observed at the micro-nano interface region. Net volume charge …
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Novel mechanisms of endothelial-epithelial interactions underlying cancer metastasis
… through thin cytoskeletal projections called nanoChannels (nCs) that is involved in pathological angiogenesis and that may prime metastatic spread. Metastatic cells preferentially form nCs with the endothelium, enabling rapid and directed transfer of intracellular contents. Proteins, small …
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Design, Fabrication, Testing of CNT Based ISFET and Characterization of Nano/Bio Materials Using AFM
… is investigated and used for creating nanochannels on silicon surfaces. Since AFM based nanomanipulation and nanomachining is highly controllable, nanochannels are precisely scratched in the area between the source and drain of the FET where the inversion layer is after the ISFET is …
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Modeling the interface between biological and synthetic components in hybrid nanosystems
… live bacteria; (2) protein transport through a nanochannel; (3) deriving the Langmuir constant for adsorption for small, organic molecules on synthetic surfaces; (4) creating a multiscale model for transport in micro- and nanofluidic devices; (5) synthetic analogs of biological ion channels. It …
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Thermal Management Using Liquid-vapor Phase Change in Nanochannels
… in ∼728 nm height cross-connected buried SiO2 nanochannels, with micropores of diameter ∼2 μm at each intersection, is accomplished. The micropores allow water from a droplet placed on the surface to wick into the channels as well as allow thin-film evaporation from a meniscus. Experimental …
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Positronium in the AEgIS experiment: study on its emission from nanochanneled samples and design of a new apparatus for Rydberg excitations
… thesis Ps cooling and emission into vacuum from nanochannelled silicon targets was studied by performing Time of Flight measurements with a dedicated apparatus conceived to receive the slow positron beam as produced at the Trento laboratory or at the NEPOMUC facility at Munich. Measurements were …
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Molecular Interfaces and Heterogeneous Bubble Nucleation From Heated Surfaces At Nanoscale
… developed on a 2D temperature distribution in a nanochannel. The pre-trained model can be helpful in case direct measurement is not possible, like nucleation temperature on thick non-metallic surfaces.</p>
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Influence of external environment on fluid/ion transport in confined nanoscale systems
… the microporous membrane interconnected with nanochannel. I tackled this problem by using a detailed 2-D nonlinear, nonideal ion-selective model. Further, I discuss the necessary governing equations required to model the system. The model illustrates a constant conductivity in the overlimiting …
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