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Showing 1 to 3 of 3 for “"NaDC1"”.
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Molecular transport properties of sodium/dicarboxylate cotransporters
The Na+/dicarboxylate cotransporter (NaDC1) plays important roles in absorption of citric acid cycle intermediates from the intestinal and renal tubular lumen. NaDC1 influences the homeostasis of citrate, which may be associated with the formation of kidney stones. The studies in this dissertation …
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Structural and functional studies of sodium/dicarboxylate cotransporters
The sodium/dicarboxylate cotransporter (NaDC1) is found on the apical membrane of the kidney proximal tubule and the small intestine. It carries various di- and tri- carboxylates such as succinate, á-ketoglutarate and citrate. NaDC1 is involved in regulating the concentration of tricarboxylic acid …
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Substrate specificity and functional characterization of sodium/dicarboxylate cotransporters
… transporters, mouse (m) and rabbit (rb) NaDC1, and functional characterization of a high-affinity NaDC transporter from Xenopus laevis, xNaDC3. \r\n\r\nAlthough sharing strong sequence identity, mNaDC1 and rbNaDC1 differ in their ability to transport certain dicarboxylates. For example, …