Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"NY-ESO-1"”.
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Employing T Cells For Antigen Presentation: Role of Ny-Eso-1+ T-Apc Vaccine In Multiple Myeloma
… improved outcomes. Combined immunotherapy with NY-ESO-1<sup>+</sup> CAR T cells (TCR mimetic) and an NY-ESO-1 specific T-APC vaccine in myeloma patients may lead to enhanced anti-myeloma efficacy due to improved persistence of the CAR T cells.</p> <p><strong>Materials and Methods</strong>: Using …
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Cellular and Molecular Aspects Of Naïve T cell Priming for Adoptive Immunotherapy
… MART1/Melan A as well as the germ-line antigen NY-ESO-1. Building on previous work from the host laboratory, we demonstrate that naïve expansion in high dose IL-15 improves expansion numbers but leads to a loss of ‘naïve-like’ phenotype, in particular lymphoid homing receptors CD62L and CCR7 as …