Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"NXF"”.
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The role of human and Drosophila NXF proteins in nuclear mRNA export
… This family was termed nuclear export factor (NXF) family. While the yeast genome encodes only one NXF protein (Mex67p), the genomes of higher eukaryotes encode several NXF proteins. There are two nxf genes in C. elegans and A. gambiae, four in D. melanogaster, and at least four in H. sapiens …
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A link between c. Elegans morphogenesis and mrna export
… t2160 mutant allele of nuclear export 1, nxf-1. nxf-1/TAP encodes a protein that is required for mRNA export from the nucleus to the cytoplasm. To better understand the role of NXF-1 in C. elegans embryonic morphogenesis, we analysed the expression of several apical junction markers in …
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Tap /Nxf1 N -Terminal Domain Mediates Homotypic Complex Assembly and Is Necessary for Nuclear RNA Export
Tap/NXF1 is the metazoan nuclear export receptor for both poly (A+) RNA as well as cellular and viral RNAs containing the constitutive transport element (CTE). Tap is a multi-domain protein that interacts directly with nucleoporin proteins of Nuclear Pore Complexes (NPCs) as well as messenger RNA …
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Cellular Phenotypes Associated with NRXN1 Mutations in Autism; an iPSC Study
… of NRXN1 expression compared to patient line 092_NXF. 211_NXM neurons also displayed significantly higher firing rates as determined by MEA recordings. Conversely, patient line 092-NXF had NRXN1 expression and neurons with aberrant neurite outgrowth. I also generated four different NRXN1- mtant …