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Showing 1 to 15 of 15 for “"NT-3"”.
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Die Konzentrationen von Brain-Derived-Neurotrophic-Factor (BDNF) und Neurotrophin (NT 3) in humanem Hirngewebe bei der Demenz vom Alzheimer-Typ und Psychosen aus dem schizophrenen Formenkreis
In der Vergangenheit wurden zahlreiche Untersuchungen durchgeführt, um die Bedeutung Neurotropher Faktoren (NTF) in der Pathogenese der Alzheimer Demenz bzw. schizophrener Psychosen besser zu verstehen, um daraus therapeutische Schlüsse zu ziehen (Hefti und Weiner, 1986; Koliatsos et al., 1991; …
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Inhibition of Retinoic Acid Receptors Results in Defasciculation of the Trigeminal Nerve in Xenopus laevis
… nervous system has been studied for over a century, yet surprisingly little is known about how the nerves are guided to their targets. The study of the development of these nerves has important implications for our understanding of craniofacial anomalies and possible treatments for both injury …
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Sustained Release of Growth Factors from Hyaluronic Acid Hydrogels and Polyethylene-Glycol Microparticles for Axonal Growth
The central nervous system, unlike other tissues, lacks the ability to spontaneously regenerate. During spinal cord injury, the disruption of axonal pathways is one of the main causes of functional loss. Neurotrophin-3 (NT-3) and insulin-like growth factor-1 (IGF-1) are two growth factors that have …
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Der Einfluss von neurotrophen Faktoren auf das biologische Verhalten von Medulloblastomen
… das biologische Verhalten von Medulloblastomen unter dem Einfluss neurotropher Faktoren untersucht. Diese verwendeten Neurotrophine wirken innerhalb der untersuchten Medulloblastom-Zellinien und –Primärkulturen in unterschiedlicher Weise auf Proliferation, Migration und das Invasionsverhalten der …
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Entwicklung von Merkelzellen in der Haut von P0-defizienten Mäusen
… für die distale Innervation in P0-defizienten Mäusen, ein Tiermodell der hereditären motorisch-sensorischen Déjérine-Sottas-Neuropathie, die Merkelzellzahl in der Haut dieser Tiere untersucht. Zusätzlich wurde untersucht, ob durch den Gendefekt das unmyelinisierte Nervenfasersystem der …
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Development of Combinatorial Strategies Employing Neural Stem Cells and Polymer Scaffold for Spinal Cord Repair
"ABSTRACT- Development of Combinatorial Strategies Employing Neural Stem Cells and Polymer Scaffold for Spinal Cord Repair Stem cell-based therapy holds promise to enhance functional recovery following spinal cord injury (SCI). Most evidence that transplantation of neural stem cells can produce …
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Bedeutung des "vasodilator-stimulated phosphoprotein" (VASP) für die Entwicklung des Hörvermögens von Säugetieren - eine experimentelle Studie an Mäusen -
… der Ena/VASP Proteinfamilie, gilt als ein entscheidender Faktor bei der Regulation von Aktindynamik. Es ist an Zellbeweglichkeit und –adhäsion, unter anderem in Filopodien und dem Wachstumskegel auswachsender Neurone beteiligt. Anhand dieser Beobachtung wurde die Rolle von VASP für das …
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Therapeutic Effects of Human Mesenchymal Stem Cells on Traumatic Brain Injury in Rats: Secretion of Neurotrophic Factors and Inhibition of Apoptosis
… brain insults, which often result in permanent functional loss of damaged cells. Many researchers have looked for methods that will reduce secondary brain damage since there is no effective therapeutics to recover functional loss of damaged tissues. The severity of the secondary mechanism of …
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Early Effects of Organophosphate Compounds on In Vitro Intracellular Signaling and Levels of Active Neurotrophin Receptors, and on In Vivo Neurotrophin Concentrations
… (OP) compounds are found in household pest control products, plastics, and petroleum. Due to the neurotoxic nature of OP compounds, exposure can cause both acute and delayed symptoms, including organophosphate-induced delayed neuropathy (OPIDN). This syndrome is characterized by Wallerian-like …
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Role of the Neurotransmitter Glutamate in Neural Stem and Progenitor Cells Differentiation into Oligodendrocytes
… of the mammalian brain, including the subventricular zones (SVZs) of the hippocampus and the dentate gyrus (DG), contain niches of undifferentiated neural stem and progenitor cells (NSPCs) which persist from development, all throughout adulthood. These cells can differentiate into the three …
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Escherichia coli Mastitis in the Dairy Bovine
Diagnosis techniques and treatments for Escherichia coli mastitis in the dairy bovine were evaluated in two experiments. The first experiment evaluated eosin methylene blue agar as a method of distinguishing E.coli from other gram-negative mastitis pathogens. Escherichia coli will usually produce a …
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SEQUENCE ELEMENTS ESSENTIAL FOR RNA EDITING IN CHLOROPLASTS
Organellar transcripts of angiosperms contain cytidines that are specifically edited to uridines. Almost all editing events lead to the restoration of a codon for a conserved amino acid instead of one predicted from the organelle genome. The sequences immediately surrounding an edited C are …
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Developing High Purity Embryonic Stem Cell-Derived V2a Interneurons for In Vitro Investigation and Transplantation Following Spinal Cord Injury
… has been attributed to plasticity in local interneuron populations, which are able to create novel circuits that bypass the inhibitory lesion to activate pre-existing motor pathways. Cell replacement strategies and growth factor delivery platforms often attempt to enhance these natural …
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TrkB and gene expression
… are a family of secreted proteins that potently regulate diverse neuronal responses. Family members include nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin 4/5(NT4/5). Neurotrophins bind the Trks receptor family (TrkA, B, C). NGF is …
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Anodic films on Bismuth
… The early stages in the formation of continuous anodic layers of bismuth oxide were studied using the technique of cyclic voltammetry. During this period, the oxide, Bi2O3, covered the surface by a process of simultaneous thickening and spreading of patches. The study of oxide nucleation …