Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 69 for “"NSs"”.
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Characterization of Innate Immune Mechanisms Against RVFV and a Potential Target for Antivirals
… of a tripartite genome (L-, M- and S- segments). NSs, encoded in the S- segment promotes degradation of PKR and general transcription shutoff including IFN-β mRNA synthesis. Currently, no effective measures have been developed to prevent or treat RVFV disease and very little is understood about …
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Characterisation of the immune modulatory effect of wild type Rift Valley fever virus strains
… wurde die IFN-β-antagonistische Funktion des NSs-Proteins von RVFV Isolaten unterschiedlicher Herkunft (Säugetiere, Menschen und Insekten) nach Klonierung und Sequenzierung des jeweiligen Nichtstruktur S-Segment (NSs) Gens untersucht. Die immunmodulatorische Funktion von NSs wurde dahingehend …
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Acute Impact of Non-Sugar Sweeteners on Glycemia in Middle-Aged and Older Adults with Prediabetes
The consumption of non-sugar sweeteners (NSS) has significantly increased over the years, particularly in middle-aged and older adults who are coincidentally at increased risk of developing impaired glucose tolerance. However, the understanding of how individual NSS impacts glycemia in this at-risk …
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The effectiveness of the National Student Survey and local institutional surveys as a management tool for setting effective strategies in higher education
… primarily the National Student Survey (NSS), accurately capture the views of students. The research endeavours to undertake a critical review of the NSS enabling the thesis, based on a case study organisation, to serve as a robust tool to guide the setting of strategy aimed at improving …
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HIJACKING OF CELLULAR PATHWAYS BY NOVEL TICK-BORNE PHLEBOVIRUS
… of interferon (IFN) responses by SFTS virus NSs has been shown to correlate with the relocation of RIG-I signaling proteins into early endosomal-derived cytoplasmic structures positive for SFTS virus NSs. Moreover, ubiquitin, an important post-translational modifier required for initiation of …
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National Security Strategy: South Korea and the Northeast Asian Context (2002-2019)
… South Korea’s national security strategy (NSS) and the broader Northeast Asian context, covering roughly the time period from 2002 to 2019 over the four South Korean presidential administrations who have publicly released their governments’ NSS. It focuses more on unpacking the country’s …
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The Impact of the Non-Structural Small Segment Gene on Host Immune Responses Against Rift Valley Fever Virus
… deletion in the S-segment non-structural gene (NSs). When used in vaccination of animals both vaccine constructs show promising results. However, extensive investigation on the fundamental differences in innate immune responses, which ultimately impact the quality, intensity and duration of host …
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Ideology, Gender Roles, and Pronominal Choice: A sociolinguistic analysis of the use of English third person generic pronouns by native speakers of Arabic
… In this study, 150 participants (50 English NSs and 100 Arabic-speaking L2 learners of English) completed two tasks: a gender role assignment questionnaire and a written sentence completion task. The goal of the first task was to examine what gender roles (i.e., typically female, typically …
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The Effects of Chinese and Spanish Writing Systems on L2 English Learners’ Vocabulary Acquisition
… speakers (NCS) and six native Spanish speakers (NSS) participated in this study. In Experiment 1, I found that NCS spelled opaque, or irregular, English words from an aural prompt more successfully than did NSS speakers. In Experiment 2, I hypothesized that because Chinese words are not processed …
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Plasmonic Nanoshells: Synthesis, Functionalization, and Photonic Applications
… application of hollow gold-silver nanoshells (GS-NSs). GS-NSs were chosen for this research because of their unique surface plasmon resonance properties, allowing for these nanostructures to be designed to absorb light at wavelengths from the visible to the near-infrared. Initial studies utilizing …
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Patterns of technology innovation in National Security Space acquisition
National Security Space (NSS) acquisition, like the space sector in general, is constantly tasked to push the frontier of technical performance while controlling program cost and schedule risk. These goals lead to a challenging policy problem in which performance increases are sought through the …
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Discovering LC3-interacting region (LIR) motifs in hemorrhagic fever viruses: Implications for host autophagy and viral replication.
… the present study. The RVFV nonstructural small (NSs) protein is the main virulence factor of RVFV and we discovered four novel LC3-interacting region (LIR) motifs within NSs (NSs1-4), indicating that NSs interacts with LC3, the host key autophagy protein. Autophagy is a cellular process that can …
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Use of plausibility information and structural preference in resolving sentence ambiguity in Korean
… L1 backgrounds: native speakers of Korean (NSs), heritage speakers of Korean (HSs), and adult second-language (L2) learners of Korean (K2s). HSs in the current study were Korean-English early bilinguals whose dominant language was English while K2s were international students and immigrants …
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OROPOUCHE VIRUS DISRUPTION OF HOST CELL FUNCTIONS: PYROPTOSIS INDUCTION AND TRANSCRIPTIONAL SUPPRESSION
… protein from the small (S) segment of OROV (OROV NSs protein) in virus-infected culture cells. Macrophages are critical in host defense, but their response to OROV infection remains poorly understood. IL-1β, a key pro-inflammatory cytokine, plays a central role in the febrile response and is …
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An Assessment of the 2002 National Security Strategy of the United States: Continuity and Change.
The 2002 National Security Strategy of the US (NSS 2002) appeared to have presented a momentous approach to self-defense. To many, the doctrine of preemptive selfdefense seemed to challenge the legal and political foundations of the post-World War II international order. Some saw in the US stated …
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Speech style, syllable stress, and the second-language acquisition of Spanish /e/ and /o/
… learners, unlike native speakers (NSs), reduce vowels in unstressed syllables and diphthongize /e/ and /o/ in stressed syllables. Additionally, it adds to previous research by investigating how speech style affects L2 Spanish vowels, how these effects change by course level, and how …
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The Role of Motivation in Second Language Pronunciation
… family as English. Fifteen non-native speakers (NNSs) of English filled out a questionnaire and produced four speech samples, including a picture description task, paragraph reading task, sentence reading and word reading task. Fifteen native speaker (NS) controls also produced the same speech …
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Development of a domestic space launch ecosystem for optimal support of US national interests
… requirements to satisfy nominal demand for NSS disaggregated constellations. Moreover, the USG will be unable to maintain space superiority in the aftermath of the eventual loss of NSS satellites due to adversary attacks and environmental events. A USG space launch enterprise system …
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Methane sulphonic acid as a tracer for non sea salt sulphate: implications for global climate regulation
… between MSA and non ea salt sulphate (nss-SOi-) may be examined and this has been investigated in amples collected at Oxford. In spite of adopting an original and more rigorous mechanism for establishing the concentration of nss-SOi- in precipitation there • till evidence that mean …
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Astrophysical signatures of neutron stars in compact binaries and experimental improvements on gravitational-wave detectors
Neutron stars (NSs) are astrophysical laboratories that allow us to probe physics at extreme conditions. The first half of this Thesis is devoted to exploring how we can connect theoretical models of NSs to observational signatures whose detections are made possible by state-of-the-art instruments. …
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