Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"NRTN"”.
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Characterisation of Prodomains in the GDNF Family
… Differentiation Factor 15 (GDF15) and Neurturin (NRTN) have wide ranging roles in biology, with potential applications in diseases such as diabetes and obesity. As members of the glial cell line derived neurotrophic factor (GDNF) family, both GDF15 and NRTN signal through the RET receptor. RET …
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Co-Signaling by Neurotrophic Factors and the Extracellular Matrix for Axonal Growth and Neuronal Survival
… (GFLs) on axonal growth. GDNF, neurturin (NRTN) and artemin (ART) but not persephin (PSPN) promoted axonal initiation in cultured DRG neurons from young adult mice. This effect required Src family kinase (SFK) activity. In neurons from GFRalpha2-deficient mice, NRTN did not significantly …
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Characterization of Murine Cardiac Cholinergic Innervation and Its Remodeling in Type 1 Diabetes.
… of the neurotrophic factor neurturin (NRTN) in the development of cholinergic innervation, because there was indirect evidence that implicated it as a crucial factor. Results from our work definitively demonstrate that NRTN plays a major role in the development of cardiac …
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Neural and Physical Niches Orchestrate Skeletal Remodelling and Promote Cartilage Regeneration
… source of the neurotrophic factor, Neurturin (NRTN), which supports osteocyte survival and growth. Loss of cholinergic innervation also led to increased expression of the Wnt inhibitor, sclerostin, in osteocytes, and inhibition of sclerostin in Gfra2<sup>-/-</sup> mice rescued deficits in bone …