Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"NR4A2"”.
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Investigating the Regulation and Function of the NR4A Nuclear Receptors in Cancer
… 4A (NR4A), which includes the NR4A1 (Nur77), NR4A2 (Nurr1), and NR4A3 (Nor-1) genes, has been implicated in adult solid tumors and has been characterized as pro-tumorigenic mediator of cell proliferation, transformation, migration, and drug resistance. Alternatively, in leukemia, NR4A1 and …
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Δημιουργία τράπεζας πληροφοριών Ελλήνων παρκινσονικών και εύρεση νέων και γνωστών μεταλλάξεων του γονιδίου NR4A2 και η λειτουργική τους σημασία
… εμφάνιση της νόσου είναι και το γονίδιο Nurr1 (NR4A2). Το Nurr1 ανήκει στην υπο-οικογένεια NGFI-B (Nerve Growth Factor-Induced clone B) των ορφανών υποδοχέων. Εκφράζεται στους πυρήνες των κυττάρων του κεντρικού νευρικού συστήματος, και ιδιαίτερα στους ντοπαμινεργικούς νευρώνες. Είναι σημαντικό …
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Role of miR-19a-3p and miR-19b-3p in microglia activation and neuroinflammation
… expression of the neuroprotective genes Nurr1 (Nr4a2) and Nur77 (Nr4a1) following microglia activation and SCI. Results: Findings from Aim 1 revealed that mimics of miR-19a or miR-19b enhanced microglia activation, indicated by increased pro-inflammatory cytokine expression and decreased SOCS1 …
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A functional study on novel genes involved in regulating aldosterone secretion in normal human zona glomerulosa and in aldosterone-producing adenomas
… in H295R cells caused an increase in CYP11B2 and NR4A2 gene expression levels but basal aldosterone secretion was unchanged. In the presence of calcium agonists, ANO4 reduced aldosterone secretion. ANO4 subcellular localisation was confirmed as cytoplasmic by immunofluorescence microscopy of …