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Showing 1 to 5 of 5 for “"NPFF"”.
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Neuropeptide FF and Neuropeptide VF and their control in the regulation of energy homeostasis and glucose metabolism
… to investigate the role of the Neuropeptide FF (NPFF) and Neuropeptide VF (NPVF) in the regulation of energy balance and glucose homeostasis. This study reveals that NPFF signalling plays important roles in fluid and glucose homeostasis, since Npff-/- mice exhibit an increased water intake and …
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Identification of Neuropeptide FF receptor 2 (NPFFR2) and its ligand NPFF as a factor to affect cancer progression
Ⅰ. 서론 1 Ⅱ. 재료 및 방법 5 A. 간암 세포주 및 세포배양 5 B. RNA 분리 및 RT-PCR 5 C. 발현 조절 및 펩티드를 이용한 수용체 활성화 6 D. Western blot 6 E. Invasion assay 7 F. Wound healing assay 7 G. Colony formation assay 8 Ⅲ. 결과 9 Ⅳ. 고찰 26 Ⅴ. 결론 30 참고문헌 31 ABSTRACT 38
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Synthesis and Evaluation of Dual-Acting Ligands for Mu Opioid And Neuropeptide FF Receptors
… these anti-opioid systems, the neuropeptide FF (NPFF) system, which is comprised of two receptor subtypes NPFF1 and NPFF2, is a member of the RFamide family and has been shown to modulate opioid activity. Although, currently, there are limited numbers of reported NPFFR ligands, it has been …
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Satiety induced by neuropeptide FF and gastrin in birds
… behavior in avian models. Neuropeptide FF (NPFF) was intracerebroventricularly (ICV) injected into Japanese quail and decreased food intake at a dose of 32 nmol. NPFF-injected quail had increased expression levels of hypothalamic melanocortin subtype 3 receptor and decreased expression …
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Design synthesis and biological evaluation of non-peptide neuropeptide FF ligands
… of a radioligand ([<super>3</super>H]-NPVF for NPFF<sub>1</sub> receptors and [<super>3</super>H]-EYF for NPFF<sub>2</sub> receptors) and were conducted for each subtype. Though some of the compounds, such as cycloheptylmethyl substituted analog, did not bind within the limits of the assay to …