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Showing 1 to 2 of 2 for “"NOX2 NADPH oxidase"”.

  1. Investigation into the mechanism of Nox2 NADPH oxidase-dependent signalling in doxorubicin cardiotoxicity

    … suggested that ROS generated specifically from Nox2 NADPH oxidase, contributes to key processes underlying cardiac dysfunction associated with chronic DOX treatment. The aim of this study was therefore (1) to characterise the role of Nox2 NADPH oxidase-derived ROS in DOX-induced cardiotoxicity …

    qu-belfast Repository record for Investigation into the mechanism of Nox2 NADPH oxidase-dependent signalling in doxorubicin cardiotoxicity (opens in a new tab)

  2. Investigating the role of NADPH oxidase 4 (NOX4) in differentiation and function of induced pluripotent stem cell–derived endothelial cells

    … with recent evidence specifically highlighting NADPH oxidases as a key source. In this thesis, we investigated the role of NADPH oxidase-dependent redox signalling in differentiation of mouse and human iPS-ECs, and provide evidence implicating ROS derived from the NOX4 isoform during the …

    qu-belfast Repository record for Investigating the role of NADPH oxidase 4 (NOX4) in differentiation and function of induced pluripotent stem cell–derived endothelial cells (opens in a new tab)