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Showing 1 to 10 of 10 for “"NOS3"”.
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Die Bedeutung von NOS3-Gen-Polymorphismen für die Ausdauerleistungsfähigkeit
… des Gens, welches für die Nitrooxidsynthetase (NOS3) codiert. Die Arbeitshypothese war, daß dieses spezielle Gen durch seine Schlüsselrolle in der Synthese von NO und seines potentiellen Einflusses auf die endotheliale Funktion möglicherweise eine Rolle spielt in der unterschiedliche …
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In Vitro Regulation of Ptgs2 and Nos3 Expression in Clonal Osteogenic Cells Following Pulsatile Fluid Flow
… changes in mRNA levels of Ptgs2 (COX-2) and Nos3 (eNOS). The pattern of Ptgs2 expression in these cell types support the hypothesis that osteocytes are the mechanosensors in bone. The data further supports the mechanism of stimulation of bone cells is fluid shear stress and the osteogenic …
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Pharmacogenetics of resistant hypertension: evaluating the role of genetic variation in ABCB1, ADBR1, CES1, CYP3A4, CYP3A5, NEDD4L, NOS3, NR3C2 and SCNN1B among South African hypertensive patient
… ABCB1, ADBR1, CES1, CYP3A4, CYP3A5, NEDD4L, NOS3, NR3C2 and SCNN1B, in the development of resistant hypertension in South African patients. Knowledge of pharmacogenetic variants that play a role in resistant hypertension may potentially improve treatment and management of hypertension in our …
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Thick Ascending Limb Nitric Oxide Production And Inhibition Of Nkcc2 Activity Are Impaired In Angiotensin Ii-Induced Hypertension
… oxide (NO) produced by NO synthase type 3 (NOS3) increases cyclic GMP (cGMP) and inhibits THAL transport by reducing Na/K/2Cl cotransporter type 2 (NKCC2) activity. Interestingly, in angiotensin II-induced hypertension, THAL NaCl transport is enhanced. However, whether this is due to a …
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The effect of single nucleotide polymorphisms of oxidative stress genes and low grade inflammation upon pulse wave contour analysis, a useful non invasive, intermediate vascular phenotype.
… and the endothelial nitric oxide synthase gene, NOS3, have an effect upon arterial compliance in patients with coronary artery disease (Chapters 4,5 and 6). In healthy volunteers, free of cardiovascular disease whether a relationship existed between markers of low grade inflammation and arterial …
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Adverse Childhood Experience-conditioned serum from young adults promotes a dysregulated endothelial cell gene expression profile
… and lower expression of Nitric Oxide Synthase 3 (NOS3) (p=0.048) than the cells that were exposed to serum from the zero ACEs group. CONCLUSION: Overall, higher expression of inflammatory mediators (ICAM1, CCL2, VCAM1), as well as decreased expression of the vasodilator NOS3 and increased …
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Investigation into the genetic nature of familial congenital bicuspid aortic valve
… trait with variable penetrance. We evaluated the NOS3 candidate gene based on the reported phenotype of a mouse mutant, and the FBLN2 and TIMP4 genes based on their role in heart development. DNA sequencing of these genes in our BAV families did not reveal the presence of any potential …
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Effects of Far Infrared Irradiation on Vascular Function in Healthy Subjects
… 1 (KEAP1) and endothelial nitric oxide synthase (NOS3) in peripheral blood mononuclear cells (PBMCs) was examined.<b><br/></b><b><br/></b><b>Results</b>: in comparison with baseline, the ACh response was significantly improved with FIR treated back following both protocols 1 and 2. There was no …
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An investigation into the capabilities and affecting factors of isometric mid-thigh pull force production in elite youth soccer players.
… force production capabilities: PPARA rs4253778, NOS3 rs2070744, COLIA1 rs2249492 and VDR rs2228570. Allele and genotype frequency was determined along with the influence of those single nucleotide polymorphisms (SNPs) on isometric MVF. Only NOS3 was different in genotype distribution between …
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Maternal and placental adaptations to hypoxia
… uterine mesometrial nitric oxide synthase-3 (Nos3) expression, a factor potentially contributing to the hypoxia-induced uterine vascular dilation. Collectively, these studies demonstrate the importance of various maternal and placental adaptive responses to hypoxia which permits proper oxygen …