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Showing 1 to 1 of 1 for “"NKB blocker"”.

  1. Kisspeptin and neurokinin B in the regulation of the human hypothalamic-pituitary-gonadal axis

    Skorupskaite, KarolinaThe University of Edinburgh2017

    … Hypothalamic kisspeptin and neurokinin B (NKB) are central regulators of GnRH and thus gonadotropin (LH and FSH) secretion. Men and women with loss-of-function mutations in NKB-kisspeptin pathway show hypogonadotropic pubertal delay with reduced GnRH/LH pulsatility. Studies in patients with …

    edinburgh Repository record