Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"NIR laser"”.
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Experimental evaluation of near infrared light penetration into neural tissue
Near infrared (NIR) lasers find applications in medicine both for diagnostic and treatment purposes. Penetration depth into the tissue is a critical parameter to be considered in these NIR laser applications. Published data on the optical properties of rodent neural tissue are rare, despite the …
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Finite element modeling of temperature elevation due to NIR exposure in neural tissue
Near infrared (NIR) lasers have been used in various types of medical applications. Heating is one of the most important concerns in the neural tissue when illuminated with NIR light. Rodent models are frequently used to study laser-tissue interactions. As a part of ongoing research project in the …
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Poly(NIPAAm-co-AAm)-gold nanoshell composites for optically-triggered cancer therapeutic delivery
… which rapidly transfer near-infrared (NIR) light energy into heat energy due to the surface plasmon resonance phenomena. When this material is loaded with absorbed drug molecules, drug release can be externally triggered by exposure to an NIR laser. Initial characterization of this …
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Ankunftszeitbestimmung ultrakurzer XUV Pulse von FLASH durch Kreuzkorrelation mit ultrakurzen NIR Pulsen
The high-gain, single-pass free-electron laser in Hamburg (FLASH) is operated in the self amplified spontaneous emission (SASE) mode. It delivers ultrashort (a few tens of fs) extreme-ultraviolet (XUV) pulses with photon energies up to 200 eV, peak powers at the gigawatt level, unprecedented …
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Synthesis, surface modifications and biomedical applications of colloidal gold nanoparticles, towards controlled regulation of angiogenesis in conjunction with photo-thermal therapy
… NPs were illuminated with near-infrared (NIR) laser light. Light at this frequency penetrates human tissue and is absorbed by associated with cells anisotropic NPs. NPs convert the absorbed light into heat, which causes an increase in the local temperature. Increased temperatures result in …
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Fluorinated Graphene Oxide: structure, morphology and its potential use in biological applications
… contrast. When irradiated with a Near Infra Red (NIR)-laser, FGO was able to exhibit photoacoustic contrast and serve as a photothermal therapy being able to ablate cancer cells in vitro. The limitation of FGO is its size (500-1000nm). Therefore, density gradient ultracentrifugation was …
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Femtosekundinių lazerio impulsų taikymas refrakcinei chirurgijai /
… for treatment of refractive errors is the laser-assisted in situ keratomileusis. The main goal of this work is to explore the possibility to replace two different laser systems (UV nanosecond and nIR femtosecond), that are currently used for the refractive corneal surgery, with a single …
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Applications of femtosecond laser pulses in refractive eye surgery /
… for treatment of refractive errors is the laser-assisted in situ keratomileusis. The main goal of this work is to explore the possibility to replace two different laser systems (UV nanosecond and nIR femtosecond), that are currently used for the refractive corneal surgery, with a single …
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Towards real-time monitoring of bacterial cultures without the need for physical sampling: elastic scattering, fluorescence and Raman spectroscopy of Escherichia coli cultures.
… fluid medium (LB/MM) in a quartz cuvette using a NIR laser (785 nm) and collecting all backscattered light from the cuvette. This approach may be useful in a broad range of academic/industrial applications that utilize bacterial cultures.</p>
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The synergistic role of light and heat in liquid-based nanoparticle manipulation
… predictions. When thermal effects dominate, laser light can induce local temperature gradients. Here, this was achieved by absorption of near-infrared (NIR) laser light in a Chromium microdisc. This resulted in thermophoretic separation of sodium azide ions, causing a local electric field …
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Applications of Ephb4 Receptor Specific Peptides In Targeted Cancer Imaging and Therapy
… TNYL-PEG-HAuNS nanopatilces with near-infrared (NIR) laser resulted in selective destruction of these cells in vitro. EphB4 targeted TNYL-PEG-HAuNS showed more photothermal killing effect on CT26 tumor model than PEG-HAuNS did. In summary, tumors with overexpression of EphB4 receptors can be …
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Microneedle array patches for skin hyperthermia and enhanced intradermal drug delivery
… to heat up a thin skin model upon Near Infrared (NIR) laser irradiation. This technology circumvents skin deposition and injection of GnRs and, thereby, the uncertainty regarding their metabolism, safety and toxicity once they reach the systemic circulation. This approach was further improved in …
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Feasibility Study of Multi-application, Multi-Walled Carbon Nanotube for Magnetic Resonance Temperatrue Imaging Guided Laser Induced Thermal Therapy
… MR contrast agents and Near-Infared Radiation (NIR) laser absorbers are combined with Proton Resonance Frequency (PRF) based Magnetic Resonance Temperature Imaging (MRTI) to improve the safety and efficacy of Laser Induced Thermal Therapy (LITT). Instilled MWCNTs enable precise tumor …
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Design strategies and application of stimuli-responsive nanoparticles for cancer diagnosis and therapy
… (10 kDa) used when treated with near-infrared (NIR) laser. Taking one step further, in chapter 3, we encapsulated NIR light-responsive indocyanine class of dye (IR-820) into polymeric NPs for the PTT of breast cancer. The optical properties of dye were preserved to obtain better photothermal …
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Temperature elevations due to NIR exposure in the brain tissue
Near infrared (NIR) lasers have been used in medical applications both for diagnostic and therapeutic purposes. Temperature elevation profile inside the tissue is a critical factor that needs to be better understood in these applications. The purpose of this study is to determine the temperature …
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Synthesis, Functionalization, and Characterization of Dominant UV Emitting Upconverting Nanocrystals and Absolute Quantum Yield and Power Dependence Metrics for the Elucidation of Upconversion Mechanisms
… science fields. Recent developments in nanosized laser materials incorporating lanthanide-doped sensitizer and activator pairs and the development of numerous crystallographic, co-dopant, morphological, and/or surface-appended optimizations to these materials have given rise to a novel class of …
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Induction of Immunogenic Cell Death via Nanoparticle-Mediated Dual Chemotherapy and Photothermal Therapy
… that can absorb the light in near infrared (NIR) region and convert it to heat. NPs were characterized and confirmed to be suitable for agent delivery. Both types of NPs were shown to significantly reduce the viability of model cancer cells, MDA-MB-231 breast cancer cells and B16F10 melanoma …