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Showing 1 to 20 of 193 for “"NIH"”.

  1. Unintended effects of changes in NIH appropriations : challenges for biomedical research workforce development

    Diaz, Mauricio GomezMassachusetts Institute of Technology2012

    The U.S. government doubled NIH appropriations between 1998 and 2003, aiming to significantly foster research activities in biomedicine. However, several indicators demonstrate not only that the impact of the budget increase fell short of expectations; in many cases it resulted in unintended …

    mit Repository record

  2. Die Rolle einer konstitutiv-aktiven MAP-Kinase SAPK-Beta bei der zellulären Transformation, Proliferation und Apoptose von NIH-3T3-Fibroblasten

    Rennefahrt, UlrikeUniversität Würzburg

    … führte zur morphologischen Transformation von NIH 3T3 Fibroblasten. Darüber hinaus bildeten diese Zellen kleine Foci aus transformierten Zellen, wuchsen in Soft-Agar und vergleichbar mit onkogenem Ras oder Raf, resultierte auch die Expression von aktiviertem SAPKb in der Zerstörung des …

    wurz-thes Repository record

  3. Evaluating educational bias in executive function assessments: A comparison of ReacStick and the NIH Toolbox in individuals with multiple sclerosis

    Lane, Maura2026

    … of Health Cognition Toolbox Cognition Battery (NIH Toolbox-CB)— in individuals with multiple sclerosis (MS). Participants with confirmed MS diagnoses completed both cognitive assessment tools, and the correlation between years of education and task performance was analyzed to evaluate the …

    emich Repository record

  4. PROGETTAZIONE E SINTESI DI LIGANDI IBRIDI SIGMA-NO LIGHT-ACTIVATED A POTENZIALE ATTIVITA ANTIPROLIFERATIVA. NIH 10495 E DERIVATI: MODULAZIONE DELL ATTIVITA OPPIOIDE, SIGMA-1 ED HDAC NEL DOLORE NEUROPATICO.

    ZUCCARELLO, ELISAUniversità degli studi di Catania2015

    … Medzhiradsky e Winger sul ligando oppioide NIH10495, strutturalmente correlato all Aloperidolo, al fine di differenziarne l effetto sul sito di legame della Fenilciclidina con 3H-TCP come radioligando e con 3H-(+)SKF 10,047 per esaminare la loro affinità sul sistema recettoriale sigma1 …

    catania Repository record

  5. Bridging the gap between undergraduate and doctoral education in STEM: A mixed methods evaluation of the NIH Postbaccalaureate Research Education Program (PREP) at a highly selective private university in the northeast

    Rashid, NaureenUniversity of Illinois at Urbana-Champaign2022

    Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01

    uiuc Repository record

  6. Does decreased research funding from the National Institutes of Health to local academic hospitals cause an increase in industry sponsored research funding?

    Truesdell, John A., Jr. (John Alan)Massachusetts Institute of Technology2011

    The National Institutes of Health (NIH) has been the stalwart of research funding at universities and academic teaching hospitals. However, since the start of the last decade NIH funding has contracted in real terms. Anticipating future Federal Government fiscal austerity, the situation appears …

    mit Repository record

  7. ARE GRADUATE STUDENTS RATIONAL? MACROECONOMIC DETERMINANTS OF GRADUATE ENROLLMENT AND COMPLETIONS IN THE BIOMEDICAL SCIENCES

    Clack, John

    The National Institutes of Health (NIH) budget doubling from 1998 through 2003 stimulated demand for biomedical scientists, increasing both relative wages and employment. However, because research doctorates in these fields may take six years or more to complete, there is a substantial lag in the …

    unm Repository record

  8. Use of a Pre-Employment Multitasking Instrument and Neuropsychological Measures to Predict Field Performance in Police Officers

    Galusha, Jeanine Marie2019

    … Texas police officers were administered the NIH Toolbox Cognition and Emotion Batteries along with several traditional neuropsychological measures of attention, working memory, and mental flexibility, and a subset completed the CritiCall test. Each officers' direct supervisor completed a …

    utswmed Repository record

  9. A Role for RAS in V-CRK Transformation

    Greulich, Heidi

    … by a different mechanism. v-Crk transformed NIH-3T3 cell lines were established in order to examine the effects of blocking the Ras pathway in v-Crk transformed cells. In contrast to previous studies done in mammalian cells, v-Crk caused morphological transformation and promoted …

    rockefeller Repository record

  10. Suppressor of cytokine signalling 3 (SOCS3) turnover and regulation of human saphenous vein smooth muscle cell signalling and function

    Moshapa, Florah T.University of Bradford2021

    Neointimal hyperplasia (NIH) is a cardiovascular disease characterised by increased smooth muscle cell (SMC) inflammation and proliferation. Suppressor of cytokine signalling 3 (SOCS3) limits Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathways involved in vascular …

    bradford Repository record

  11. Suppressor of cytokine signalling 3 (SOCS3) turnover and regulation of human saphenous vein smooth muscle cell signalling and function

    Moshapa, Florah T.University of Bradford2021

    Neointimal hyperplasia (NIH) is a cardiovascular disease characterised by increased smooth muscle cell (SMC) inflammation and proliferation. Suppressor of cytokine signalling 3 (SOCS3) limits Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathways involved in vascular …

    bradford Repository record

  12. A NEW QUANTITATIVE METHOD FOR THE DETERMINATION OF REGIONAL RATES OF CEREBRAL PROTEIN SYNTHESIS FROM L-[1 −11C]LEUCINE PET IMAGES

    Veronese, MattiaKing's College London2009

    … community at the National Institutes of Health (NIH), the primary United States Federal agency for conducting and supporting medical research. SNPM laboratories are located on the NIH campus in Bethesda, Maryland in the Division of Intramural Research of the National Institute of Mental Health …

    kings Repository record

  13. Molecular Study of Gβγ Dependent Breast Cancer Cell Migration and Invasion

    Kirui, JosephCreighton University2011

    … of cancer metastasis. Conditioned media (CM) of NIH-3T3 fibroblasts contains chemoattractants that activate different GPCRs. Expression of βARKct attenuated NIH-3T3 CM-induced migration and invasion of both metastatic breast cancer MDA-MB-231 and MDAMB-436 cells by 40-50%. Migration and invasion …

    creighton Repository record

  14. Application Of In Vivo Flow Profiling To Stented Human Coronary Arteri

    Nanda, Hitesh

    … between WSS and Neointimal Hyperplasia (NIH) in two groups of diabetic patients after being treated separately with bare metal stents (BMS) and Sirolimus Eluting Stents (SES). The stent assignments were blinded until the end of the study. The study was repeated for the patients after 9 …

    ucf

  15. The economic and clinical outcomes and policy implications of gene expression profiling in breast cancer care

    Oestreicher, Nina2004

    … at the Netherlands Cancer Institute to NIH guidelines in a cohort of 44 year-old women with early stage breast cancer. We utilized a decision analytic model that was informed by empiric and literature-based estimates, and model parameters were varied in sensitivity analyses. As an input …

    washington Repository record

  16. Essays on Biomedical Innovation

    Greenblatt, Wesley H.Massachusetts Institute of Technology2023

    … Programs of the National Institutes of Health (NIH) during the turbulent period surrounding the Vietnam War. I find program participants entered research-focused positions at higher rates and garnered more publications, citations and grant funding than synthetic controls. In particular, the …

    mit Repository record

  17. Neuropharmacological Mechanisms Underlying Incentive Salience and Stress

    Robinson, Shivon2016

    … thesis utilized the novelty-induced hypophagia (NIH) test, a motivational conflict paradigm, to examine the effects of stress on neural processes associated with the attribution of incentive salience to salient stimuli. Using in vivo microdialysis, we assessed the role of nucleus accumbens (NAc) …

    penn Repository record

  18. A role for glutathione in reactions between oxidants and proteins

    Mallis, Robert2000

    … of H-Ras on four cysteine residues;Within NIH/3T3 cells overexpressing H-Ras, H-Ras was S-glutathiolated on multiple thiols by diamide. At least one of the cysteine residues modified in cells by diamide is normally lipidated, suggesting a role for oxidation in regulating the membrane …

    iastate Repository record

  19. Ren as a Guideline for Solving Military Medical Ethics Violations in S.E.R.E.

    Diaz, ChloeTexas State University2019

    … for exposure to trauma in combat (APA, NIH MedlinePlus). In fact, as many as 21% of Iraqi war veterans are affected by PTSD (NIH MedlinePlus). Evidently, PTSD is a widespread issue within all branches of the military. To remedy the high risk of PTSD that military personnel are subjected …

    texas-state Repository record

  20. EVIDENCE EVALUATION IN BIOMEDICAL KNOWLEDGE GRAPHS FOR PHARMACEUTICAL DISCOVERY

    Yang, Jeremy[Bloomington, Ind.] : Indiana University2022

    … empirical bioassay data from PubChem and the NIH Molecular Libraries Program to recognize patterns of promiscuity (non-selectivity), associated with molecular scaffolds. KGAP combines data from two NIH programs, LINCS (Library of integrated network-based cell signatures), i.e. genomic …

    iu Repository record

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