Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"NHEK"”.
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Alteration of differentiation and growth of normal human epidermal keratinocytes by benzo[a]pyrene and arsenic
Normal human epidermal keratinocytes (NHEK) were chosen as an in vitro model for mechanistic studies into how altered regulation of differentiation may play a role in the malignant transformation process in human cells. Initially, the cytotoxicity of four petroleum-derived hydrocarbons …
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Composite Diaphragm Inflation: A Method for Probing the Rheological Functions of Cell -Cell Anchoring Junctions and Cytoskeletal Networks Within a Living Normal Human Epidermal Keratinocyte Sheet
… diaphragm inflation (CDI). Sheets of living NHEKs were reconstituted in vitro on tensed but highly compliant, freestanding polydimethylsiloxane (PDMS) elastomer membranes, 5.0 mm in diameter and 10.0 mum thick. NHEK-PDMS composite diaphragm (CD) specimens were then subjected to a series of …
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Effects of arsenic and UVB radiation on induction of cyclin D1 in human keratinocytes.
… using Normal Human Epidermal Keratinocytes (NHEK) to identify the effect of arsenic and UVB on humans and whether they work synergistically. We find that although both cause induction of cyclin D1, culturing cells with both co-mutagens does not lead to a potentiated effect. Evidence from …
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Tissue engineering of co-cultured skin substitutes using biocomposite membranes based on collagen and polycaprolactone
… normal human epidermal keratinocytes (NHEK), and primary human epidermal keratinocytes (PHEK) and dermal fibroblasts (PHDF) in vitro respectively. The 1:20 collagen: PCL materials exhibiting good cell growth curves and mechanical characteristics were selected for engineering of skin …
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Heat stress: A risk factor for skin carcinogenesis
… Primary adult human epidermal keratinocytes (NHEK) and ex vivo punch biopsies of normal human skin called NativeSkin® (Genoskin, France), were used as experimental models for this study. A UV cabinet fitted with a TLUVB Narrowband lamp (Philips, GERMANY), with a spectral output of 290 -315 nm, …
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Untersuchungen zur Wirkung von 2,2´-Dichlordiethylsulfid (Schwefellost) in primären und immortalisierten epithelialen Zelllinien
… epitheliale Zelllinien (A 549, SCL II, HaCaT und NHEK) wurden eingesetzt, um den Effekt von Schwefellost auf Proliferationsverhalten, Vitalität und Zytokin-Sekretion näher zu untersuchen. In den Versuchen konnte gezeigt werden, dass eine Schwefellost-Exposition bei allen vier untersuchten …