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Showing 1 to 7 of 7 for “"NHE3"”.
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Characterization of Na+/H+Exchanger-3 (Nhe3) in the Gills of Longhorn Sculpin (Myoxocephalus Octodecemspinosus)
Acid-base regulation is a vital mechanism in homeostasis. Fish must maintain optimal physiological acid-base parameters during changes in an aquatic habitat. Environmental factors such as changes in salinity affect fish ability to maintain optimal blood plasma ion concentrations. Ion regulation …
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Mechanisms of Regulation of Proximal Tubule Sodium Transporters in Obesity-Induced Hypertension
… expression and activity of Na,K-ATPase and NHE3 were increased in obese rats compared to lean rats. Moreover, in OP rats more NHE3 was associated with its active pool located in the microvillus region. Together, these results suggest that hypertension in obese rats is characterized by the …
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The Role of Dysfunctional Na+/H+ Exchange in the Development of Dysbiosis and Subsequent Colitis
… border, mediated by sodium hydrogen exchanger 3 (NHE3). NHE3 is inhibited during active IBD, but its loss in knockout animals is also enough to promote spontaneous colitis in a microbiome-dependent fashion. This dissertation investigates the specific contribution of the microbiome in NHE3 knockout …
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Estrogen Receptors and Estrogen-Regulated Genes in the Male Reproductive Tract
… epithelial ion transporters, Na+/H+ exchanger-3 (NHE3), and then influences the passive transepithelial water movement in efferent ductules. In addition to its regulation of Na + transport, estrogen also maintains epithelial morphological differentiation in efferent ductules of the male. Moreover, …
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The Role of Estrogen Receptor Alpha in Epididymal Sperm Structure and Function
… regulation were analyzed. The levels of NHE3, as well as carbonic anhydrase XIV and NBC1 were all reduced in the initial segment of the ERalphaKO epididymis, while other components appeared unaffected, including other ion transporters and V-ATPase. To determine the effect of the altered …
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Role of Phosphorylation In The Regulation of Prmt5
… protein that regulates the sodium ion exchanger NHE3. Through this interaction, PRMT5 is placed in close proximity to the membrane and therefore may regulate the influx of ions through selective ion channels. Overall, we hypothesize that the direct interaction of PRMT5 with selected partners …
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Renal Epithelial Sodium Channel (ENaC) Regulation of Pregnancy Mediated Hemodynamic Adaptations: Mechanistic Insights
… were seen in pre-macula densa transporters (NHE3, NKCC2). The similar changes observed in the distal convoluted tubule and renal collecting duct promote Na and water retention. The changes in these transporters may explain the similar plasma volume expansions previously described in pregnant …