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Showing 1 to 8 of 8 for “"NGR"”.
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Platinum-NGR A Peptide Targeting Conjugate Of Cisplatin: Design, Synthesis, And Efficacy In Breast Cancer Cells
… study we synthesized a platinum-Asn-Gly-Arg (NGR) peptide conjugate with a long-term goal of reducing adverse effects in patients, as well as combating possible drug resistance compared with other widely available platinum-based chemotherapeutics. NGR peptide motifs are specific to angiogenic …
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Peptide Targeting of Platinum Anti-Cancer Drug and Synthesis of Water Soluble Monofunctional Pt(II) Complexes Useful for Biological Labeling
… Pt(II) conjugates were synthesized having the NGR and LHRH targeting motif. The platinum conjugates bearing the NGR motif revealed selective delivery and destruction of cancer cells that had CD13 receptors compared to untargeted carboplatin drug. The development of targeted chemotherapeutic has …
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Chemical Inhibition of Nitrification: Evaluating Methods to Detect and Characterize Inhibition and the Role of Selected Stress Responses Upon Exposure to Oxidative and Hydrophobic Toxins
… respirometry and nitrate generation rate (NGR), are still the fastest and easiest methods to use. Because several conventional methods exist, we also investigated differences between differential respirometry and a UV method we developed to measure NGR. During these tests, we showed that …
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Defining effective fiber content of dairy rations
… Acetate:propionate (APR) and non-glucogenic (NGR) ratio were not affected by fiber additions. RFD was reduced for ALF compared to OG whereas CSH was higher than OG and ALF. Reduced RFD was associated with reduced total CT for ALF. RSD was not affected by fiber additions. Chopped OG was …
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Kinky structures
Rotational springs are not widely used in structural engineering other than within undergraduate texts to aid with the understanding of strut buckling or other similar theoretical exercises.The inclusion of rotational springs can significantly alter the behaviour of a structure, bringing several …
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Optimization of Biological Nitrogen Removal From Fermented Dairy Manure Using Low Levels of Dissolved Oxygen
… 1.3 mg/L. A series of nitrite generation rate (NGR) experiments confirmed the presence of an inhibitor in fermented dairy manure. A model sensitivity analysis determined that the most sensitive ammonia oxidizing bacteria (AOB) kinetic parameters were the maximum specific growth rate, , and the …
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An evaluation of indicators of prospectivity and potential mapping of porphyry deposits in middle and southern British Columbia by a GIS study of regional geochemical and other geoscientific data.
… of the National Geochemical Reconnaissance (NGR) surveys map sheets. In such cases, the data for stream sediment and water samples were levelled prior to statistical or GIS analysis. For levelling the geochemical data, a method was presented to estimate the required width for the bands that …
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Synthesis, characterization and applications of peptide-coated nanoparticles
… 1) RGDFFF to target vasculature via RGD, 2) NGRFFF to target vasculature NGR, and 3) EKHFFF to target low pH of the tumor via isoelectric point of the peptide. Chapter 1 presents the synthesis and characterization of peptide-coated NPs. The NPs were synthesized via a nanoprecipitation method, …