Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 84 for “"NGF"”.
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Type I PIP5Kα negatively regulates NGF-induced neurite outgrowth in PC12 cells
… outgrowth induced by nerve growth factor (NGF) was more prominent in PIP5KIa-deficient cells than in control miRNA-expressing cells. Reintroduction of PIP5KIα into the PIP5KIα-deficient cells attenuated NGF-induced neurite outgrowth. Similar to the neurite changes, PIP5KIα deficiency …
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Der Einfluß der Neurotrophine NGF und BDNF auf die Migration humaner eosinophiler und neutrophiler Granulozyten
… sind. Neurotrophine, zu denen u. a. NGF (nerve growth factor) und BDNF (brain-derived neurotrophic factor) zählen, werden von zahlreichen Immunzellen gebildet, und können auf diese wiederum über spezifische Rezeptoren wirken. Außerdem wurden bereits mehrfach im Rahmen immunologischer …
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Μελέτης [sic] της αγγειογενετικής δράσης του νευρικού αυξητικού παράγοντα (NGF) σε μοντέλο ισχαιμίας οπίσθιων άκρων κονίκλων
… αρτηριοπάθεια. Ο νευρικός αυξητικός παράγοντας (NGF) υπάρχουν αναφορές ότι έχει σημαντικό ρόλο στη φυσιολογική και παθολογική αγγειογένεση. Βασισμένοι σε αυτές τις παρατηρήσεις, υποθέσαμε ότι ο NGF μπορεί να επάγει το σχηματισμό λειτουργικών αιμοφόρων αγγείων σε μοντέλο ισχαιμίας οπισθίων άκρων …
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Nerve growth factor regulates Na+ transport in human airway epithelial cells
Nerve growth factor (NGF) was discovered for its ability to enhance nerve growth, but recent evidence suggests there is a correlation between elevated NGF levels in the lung and airway diseases, including lung inflammatory diseases and respiratory virus infections. NGF can be produced and act upon …
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Interactions of Thyroid Hormones, Nerve Growth Factor and Its Receptors in Development and Plasticity of the Rat Olfactory Bulb
Hypothyroidism decreased levels of olfactory bulb NGF, while up-regulating NGF receptors, p75$\sp{\rm NTR}$ and trkA in the glomerular region. We propose that decreased bulbar NGF results in decreased trophic support for specific NGF responsive cells, leading to compensatory up-regulation of NGF …
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Regulation of Cerebellar Purkinje Cell Development: Interactions Between Trophic Factors and Neurotransmitters
… that in the cerebellum. Nerve Growth Factor (NGF) and NGF receptors are highly expressed during late embryonic and early postnatal development, suggesting that NGF may play an important role in cerebellar ontogeny. However, while receptor had been localized to some cerebellar populations, …
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Numerical green's function in surface integral equation method and hydrodynamic model for solar cell analysis
Several aspects of numerical Green's function (NGF) in the surface integral equation (SIE) method for inhomogeneous media have been addressed, including the process of solving for the NGF from differential equation, the integrating of NGF with SIE, the NGF based augmented-electric field integral …
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Determining the role of nerve growth factor-beta in seminal plasma on bovine reproduction
Nerve growth factor-β (NGF) is a protein found in the seminal plasma of a variety of mammalian species. While initially known for regulating neuronal survival and differentiation, it was later discovered to interact within the endocrine and reproductive systems as well. Most notable is its function …
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Expression und Funktion von Caveolin bei glialen Zellen, insbesondere Oligodendrozyten
… konnte eine Lokalisation des hochaffinen NGF (nerve-growth-factor) Rezeptors TrkA innerhalb von CMD sowie eine direkte Interaktion von Caveolin und TrkA nachgewiesen werden. Die Rolle von CMD bei der NGF regulierten Signaltransduktion, die die Myelinbildung im ZNS steuert, scheint von der …
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The morphology, neurochemistry, and consequences of sympathosensory plexuses
… of neurotrophins such as nerve growth factor (NGF). One population of neurons that rely heavily on NGF for axonal growth and survival is the postganglionic sympathetic neurons. Trauma or disease resulting in injury to the peripheral nervous system causes an increase in the levels of this …
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Localization of nerve growth factor-β in the stallion reproductive tract
Nerve growth factor-β (NGF-β) is a protein produced in the reproductive tract of camelids (camels, llamas, and alpacas) that has been identified as the ovulation inducing factor in seminal plasma. NGF-β from seminal plasma deposited into the reproductive tract of the female camelid acts …
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Orthodontic tooth movement and neurotrophins in the rat dento-alveolar complex.
… member of the family, Nerve Growth Factor (NGF), is a polypeptide essential for supporting cholinergic innervation in the brain and sympathetic and sensory innervation in the peripheral tissues. Within the dento-alveolar complex, the function and localization of neurotrophins and their …
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Interactions of Thyroid Hormones and Nerve Growth Factor in Normal Development of the Rat Hippocampus and Basal Forebrain and in Recovery From Early Hypothyroid Retardation
… hypothyroidism results in decreased hippocampal NGF levels, while up-regulating its receptors: the p75 neurotrophin and p140 trk A receptor. We propose that declining levels hippocampal NGF results in decreased trophic support for basal forebrain cholinergic neurons, leading to a compensatory …
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Determining the Effects of Nerve Growth Factor Supplemented In-vitro Fertilization Media on Bovine Embryo Development
… lower pregnancy rates. Nerve growth factor-beta (NGF), however, has been previously shown to improve 48-hour cleavage rates and the number of hatching/ hatched blastocysts out of total presumptive zygotes. We hypothesize that NGF will improve IVP embryo development by positively influencing …
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Perineural Invasion in Oral Squamous Cell Carcinoma and Salivary Gland Malignancies: Incidence, Prognostic Impact and Molecular Insight
… factors such as nerve growth factor (NGF) and its high affinity tyrosine kinase A (TrkA) receptor have been identified as being possibly of importance in PNI. The PI3K/Akt signalling pathway is a well-established driver of cancer progression, however, the mechanism of NGF-induced Akt …
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Effects of nerve growth factor on TGF-Beta,Smad signal transduction in PC12 cells
… the other. In the present work, the crosstalk of NGF and TGF-ß/Smad signaling pathways is characterized in rat pheochromocytoma cells (PC12) which are frequently used as a model system for neuronal differentiation. PC12 cells were found to be unresponsive to TGF-ß due to limiting levels of TßRII. …
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Effects of tumor necrosis factor alpha on nitric oxide synthase in nerve growth factor-responding cells
… by a decrease in nerve growth factor (NGF)-responsive cholinergic neurons. I report a synergistic effect of the cytokine tumor necrosis factor alpha (TNFa) and NGF on expression of nitric oxide synthase (NOS), in rat pheochromocytoma PC12 cells. NGF/TNFa-promoted iNOS can be toxic in …
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Voluntary Exercise and Neurotrophin Signaling Affect the Development and Presentation of Painful Neuropathy
… found increased levels of nerve growth factor (NGF) protein, a neurotrophin known to mediate pain signaling, in the periphery, while exercise normalized these levels. Furthermore, prediabetes resulted in a switching of axonal phenotypes in the skin, increasing peptidergic nerve fibers, which was …
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Growth Factor Delivery From Fibrin Matrics Containing Affinity-Based Delivery Systems To Treat Peripheral Nerve Injury
… and biological activity of nerve growth factor: NGF) in vitro. The ABDS presented biologically active NGF, which promoted neurite extension regardless of peptide binding affinity for heparin. The efficacy of the ABDS in vivo to promote nerve regeneration in a rat sciatic nerve critical defect was …
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