Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"NFkappaB"”.
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Molecular Mechanisms of Transcriptional Synergy Between the Estrogen Receptor and NFkappaB in Breast Cancer.
… Synergy Between the Estrogen Receptor and NFkappaB in Breast Cancer.
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Regulation of Interleukin -6 Gene Expression in the Brain of Aged Mice
… old mice by gel mobility shift assay. Whereas NFkappaB activity was increased in aged brain, NF-IL-6, MRE and AP-1 were either unaffected by aging or decreased. Inhibition of increased NFkappaB activity both in vivo and in vitro decrease IL-6 mRNA expression and protein level. These results …
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Tumor Necrosis Factors and Chemokines in Hair Development
… were truly transcriptional target genes of Eda/NFkappaB and to study their functional relevance in ectodermal organogenesis, in particular in hair follicle development. Based on these studies, we were able to confirm some Wnt pathway members, such as Dkk4 and Lrp4,TNF family member A20, and two …
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The Role of Lipoprotein(a)/Apolipoprotein(a) in Endothelial Dysfunction: Mechanistic Studies in Vascular Endothelium
… this allows the nuclear translocation of NFkappaB with attendant effects on the transcription of pro-inflammatory genes. Taken together, our findings may facilitate the development of new drug targets for mitigating the harmful effects of Lp(a) on vascular EC which corresponds to an early …
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Pesticides and Pesticide Mixtures Induce Neurotoxicity: Potentiation of Apoptosis and Oxidative Stress
… found to have increased in the expression of NFkappaB activity in the nucleus. These data support the hypothesis that oxidative stress was induced in neuronal cells by exposing to these pesticides in vitro. Taken together, the results of this study support the above hypothesis and suggest that …
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Mechanisms of Exercise-Mediated Restoration of Renal Dopamine D1 Receptor Function in Aging
Renal dopamine plays a pivotal role in the maintenance of sodium homeostasis and blood pressure. Dopamine by activating D1 receptors (D1R) and inhibiting sodium transporters, Na, K-ATPase and Na, H exchanger, in renal proximal tubules (RPTs) promotes sodium excretion and thus maintains sodium …
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Die Hämatopoetische Progenitor Kinase (HPK) 1 und NFAT-Transkriptionsfaktoren unterstützen die Apoptose von T-Lymphozyten
Die Expression der Hämatopoetischen Progenitor Kinase 1 (HPK1), einem Mitglied der Familie der „Germinal Centre“ Kinasen, ist im adulten Organismus auf die Zellen des hämatopoetischen Systems beschränkt. Die HPK1 wurde ursprünglich als ein Aktivator des JNK-Signalübertragungsweges beschrieben [Hu …