Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"NF-κB essential modulator (NEMO)"”.
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ASSESSING MUTATIONS IN A ZINC FINGER DOMAIN OF NF-κB ESSENTIAL MODULATOR (NEMO) USING MOLECULAR DYNAMICS SIMULATIONS
Molecular dynamics (MD) simulations permit the probing of biomolecular systems in
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Characterization of novel immunomodulatory proteins encoded by parapoxvirus ORF virus
… Medicine as a preventive and therapeutic immunomodulatory agent. However, the functions (genes, proteins, and mechanisms of action) involved in immunomodulation remain poorly understood. ORFV establishes infection of keratinocytes in a proinflammatory environment triggered by skin abrasions. …
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Disrupting the inhibitory Kappa B kinase (IKK) - Aurora A axis in cancer
The IKK complex is an essential regulator of the NF-κB signalling pathway. It is comprised of three sub-units; catalytic subunits IKKα and IKKβ and the catalytically inactive scaffolding protein IKKγ/NF-κB Essential Modulator (NEMO). The complex can be assembled in multiple conformations as either …
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Finding NEMO by the molluscum contagiosum virus MC159 protein and its effect on viral pathogenesis in vivo
… (MCV) is a dermatotropic poxvirus that solely infects humans. MCV infections causes benign neoplastic lesions that can persists for few months in children and adults. It is an opportunistic infection in immunocompromised patients. Currently there is no FDA approved drug available for MCV …