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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 5 of 5 for “"NDE1"”.

  1. NDE1 in the DISC1 pathway: interactions of schizophrenia-related proteins

    Bradshaw, Nicholas JamesThe University of Edinburgh2009

    … Factor E (Aspergillus nidulans)-homologue 1 (NDE1) and NDE-Like 1 (NDEL1) all have evidence implicating them as schizophrenia-related proteins in their own right. NDE1 and NDEL1 are highly similar proteins which are known to play cellular roles including microtubule function and mitosis. Their …

    edinburgh Repository record

  2. The discovery of a role of FBXO7/PARK15 in intracellular trafficking

    Bjone, HannaUniversity of Cambridge2025

    … including the Dynein regulators Lis1 and Nde1. I validated Lis1, Nde1 and the Nde1 paralog protein Ndel1 as interacting proteins of Fbxo7 by co-immunoprecipitation experiments. The results presented in this thesis show that steady state levels of Lis1 are not affected by Fbxo7, while it …

    cambridge Repository record

  3. Functional analyses of mitotic microtubule-binding complexes

    Monda, Julie KathrynMassachusetts Institute of Technology2018

    … proteins with the dynein complex, including Nde1. Here, I show that Nde1 utilizes distinct intermolecular interactions to regulate different dynein functions. I also identify a previously uncharacterized interaction between Nde1 and the 26S proteasome. Finally, I explore a potential role for …

    mit Repository record

  4. Distinct Roles for Dynein Regulatory Proteins NudE and NudEL in Brain Development

    Kemal, Shahrnaz2013

    … and intracellular trafficking. Mice null for Nde1, the gene encoding NudE, have microcephaly, whereas mice null for Ndel1, which encodes NudEL, are embryonic lethal. Additionally, Nde1 mutations have recently been shown to result in microcephaly and lissencephaly in human patients. NudE and …

    columbia-diss Repository record

  5. A New Approach To Identifying Effectors and Regulators of Small GTPases

    Bertram, JessicaUniversity of Cambridge2021

    … STAMBPL1), Rab5A (OSBPL9, TBCK), Rab9A (HPS3, NDE1), and Rab11A/B (ALS2). Furthermore, numerous novel interactors were identified for Rab1A and Rab1B, two mammalian paralogues of the yeast protein Ypt1 that are known to be key regulators in ER to Golgi trafficking and suggested to play a role …

    cambridge Repository record