Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"NDA"”.
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Characteristics of Neurodiversity-Affirming Paediatric Occupational Therapy: A Scoping Review
… pertaining to Neurodiversity-Affirming (NDA) paediatric Occupational Therapy. This was to answer the question: “What does the literature tell us about the characteristics of NDA paediatric Occupational Therapy?” Introduction: The neurodiversity paradigm is emerging in the literature and …
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Forgetting the self: nondual awareness as a key component of self-transcendent experiences
… of the type of experience. Nondual awareness (NDA)—a blurring of the distinction of self and other—is proposed as the construct best suited to these ends. Two studies were designed to improve our understanding of this construct and how it relates to STEs and ST. Study 1 was a correlational …
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An eval uati on of past cattle di ppi ng practices in the former Ve nda area of Limpopo Provi nce, South Africa: Implications for sustai nable development
… cattle dipping programme was introduced in Venda from 1915 to counter rinderpest and East Coast Fever (ECF). This study approached the sustainability of cattle dipping from environmental, economic, social and governance perspectives against the backdrop of the country’s history and political …
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Development of Monte Carlo models of a gamma-ray nondestructive assay system for nuclear material control and accountability
… theft and diversion. Nondestructive assay (NDA) via gamma-ray spectrometry is one of the most common methods employed by NMCA programs to determine the amount or composition of SNM. However, accurate gamma-ray NDA of SNM can be difficult in certain scenarios due to the complex distributions …
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Total syntheses of (±)-dracephalone A and (±)-dracocequinones A and B, progress towards a total synthesis of cassiabudanols A and B, and synthetic studies towards total synthesis of N-oxy-diketopiperazine containing natural products.
… intermolecular nitroso Diels-Alder (NDA) cycloaddition as the key step in constructing the oxazine core. In utilizing (+)-raistrickindole A as a late-stage intermediate to target (-)-haenamindole, optimization efforts of the route, especially Mukaiyama hydration and diketopiperazine …
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Probabilistic modeling of the drug development domain: A Bayesian domain-knowledge application for pharmacovigilance
… 90% of NCEs do not achieve New Drug Application (NDA) approval, and many of these failures are identified during the later, more costly phases of drug development. The exponential growth in the number of putative NCEs as a result of combinatorial chemistry and high-throughput screening has only …
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Improving the efficiency of the later stages of the drug development process : survey results from the industry, academia, and the FDA
… the Prescription Drug User Fee Act I, which mandated faster response times from the FDA in return for user fee payments to the FDA by the drug developing companies. Data on approval times for new drugs indicate that this process was indeed shortened. In contrast, the average drug development …
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The drug development process : evaluation of PDUFA I/II and investigation into reducing drug development times
… the time from filing a new drug application (NDA) to granting marketing approval (i.e. the approval phase). However, there has been no alteration in the time required to progress from an investigational new drug application (IND) to an NDA filing (i.e. the clinical phase) over this same …
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Efficient Yet Robust Privacy for Video Streaming
<p>MPEG-DASH is a video streaming standard that outlines protocols for sending audio and video content from a server to a client over HTTP. The standard has been widely utilized by the video streaming industry. However, it creates an opportunity for an adversary to invade users’ privacy. While a …
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'Post-1994 challenges facing South African NGOs : a case study of six Western Cape Non-Governmental Organizations that have a development focus'
… Taxation Laws Amendment Act 30 of 2000 and the NDA Act 30 of 3000, all participants identified the benefits of the regulatory frameworks but noted the challenges with the NDA. All NGOs provided services that promoted development. Although all participants identified that the NGOs were making an …
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Design performance specification for school buildings in the vicinity of gas flaring in the Niger Delta area of Nigeria
… of schools buildings in the Niger Delta area (NDA) where gas flaring (GF) is predominant. This excessive pollution poses the biggest challenge to indoor environments and building deterioration. School buildings in Nigeria currently follow the prescriptive specification and national building …
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Developing Detection Methods for Nitroxyl
… agent, naphthalene-2,3-dicarboxaldehyde (NDA), which removes the need for separation prior to analysis, enabling high throughput analysis. HNO released from micromolar doses of donors was then quantified by measuring changes in GSH concentration. GSH reacts with HNO to produce glutathione …
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Several new methods for the development of latent and blood fingerprints
… products of 2,3-naphthalenedicarboxaldehyde (NDA) and 2,3- anthracenedicarboxaldehyde (ADA) with analine produce favourable “red-shifts” in emission wavelengths which would make them stand out from the blue background emissions commonly obtained from paper. However, poor results were obtained …
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The accelerated approval process in oncology : an examination of the conversion rate of approved therapies to full approval
… or Subpart H approval, was added to the NDA regulations so promising products that provide a meaningful therapeutic benefit for serious or life-threatening diseases could be introduced to the market sooner, particularly for diseases or conditions where there was a great unmet medical …
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Prediction of sedimentation and bank erosion due to the construction of Kahang Dam
River impoundments continue to cause changes to the hydrological regimes of its host river. Thus, assessment and development of tools for better understanding of the sediment dynamics and riverbank erosion downstream the dam will be of great benefit to researchers and policymakers. The present …
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Algorithms for nuclear data analysis applied to safety and materials
… experiment for the non-destructive assay (NDA) of uranium samples. PALS is a widely-used non-destructive technique used to study defects and vacancies in a variety of different materials. The positron trapping at vacancies in the material results in an increased positron life- time. PALS …
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Market Heterogeneity and Drug Innovation
… counts associated with New Drug Application (NDA) approvals. Consistent with previously reported estimates, I find that a 1% increase in market size produces a 2%-6% increase in innovation entry under a traditional IIH setup. However, in closer alignment with theoretical predictions, …
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Regulatory issues concerning the preclinical testing of synthetic peptides
… type of pre-clinical studies submitted with an NDA (New Drug Application) before progressing to first-in-human studies. However, the routinely submitted studies were single and repeat dose toxicity, genotoxicity, carcinogenicity, reproductive and developmental toxicity, and often studies for …
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Pulse Train Analysis Applied to the Re-Evaluation of Deadtime Correction Factors for Correlated Neutron Counting
… cycle facilities for the non-destructive assay (NDA) of plutonium (Pu). Correlated event rates are used to quantify mass values of spontaneously fissile nuclides and derive total Pu mass. These methods are limited in accuracy by uncertainty in the deadtime correction. A pulse train analysis …
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Developing Deep-Learning Methods for Diagnosis and Prognosis of Pediatric Progressive Diseases Using Modern Imaging Techniques
… disease state with imaging findings is a standard part of patient care. However, such analysis of neuroimaging is time- and labor-intensive. Automated approaches to these tasks are needed to improve speed, accuracy, and availability. Automated medical image analysis tools based on 3D/2D deep …
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