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Showing 1 to 2 of 2 for “"ND10"”.
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Investigating the Role of Human Cytomegalovirus Protein LUNA in Regulating Viral Gene Expression during Latency
… may fulfil its role is by targeting cellular ND10 structures, known intrinsic inhibitors of herpesvirus gene expression, for disruption. In support of this, latently infected cells were found to be devoid of ND10, a phenotype that was recapitulated by the direct expression of wild-type LUNA. …
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Characterisation of PP71 homologues encoded by mammalian cytomegaloviruses
… sub-cellular structures named nuclear domain 10 (ND10). The interaction of pp71 with hDaxx is believed to promote the degradation of hDaxx, resulting in relief of repression at the HCMV major immediate early promoter. Protein pp71 has also been reported to have the unusual property of mediating …