Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 133 for “"NCI"”.
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Planning Towards Equal Spatial Accessibility of NCI Cancer Centers Across Geographic Areas and Demographic Groups in the U.S.
… designated by the National Cancer Institute (NCI) form the “backbone” of the cancer care system in the United States. Awarded via a peer-review process and being re-evaluated every 3 to 5 years, an NCI Cancer Center receives substantial financial support from NCI grants. When the quality …
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Integrating HIV-associated neurocognitive impairment screening and health services within primary healthcare facilities in South Africa
… HIV-associated neurocognitive impairment (H-NCI). These individuals may then be at an increased risk for treatment non-adherence, which leads to poor quality of life and early mortality. Despite this risk, there is a paucity in trained professionals in low- and middle-income countries with …
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The significance of the EGFR pathway in malignant pleural mesothelioma
… The COX-2 positive cell lines MSTO-211H, NCI-H2052, NCI-H2452 (mesothelioma) and A549 (lung cancer) were utilised. All cell lines were tested for EGFR, KRAS and BRAF mutations. Cells were incubated with Cetuximab, Gefitinib, Rapamycin, Ku0063794 (MTOR kinase inhibitor) and Celecoxib as …
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Evaluation of the effect of rail intra-urban transit stations on neighborhood change
… with a neighborhood change index (NCI), built on the Neighborhood Life-Cycle framework, with an adaptation that incorporates both the filtering (negative NCI) and gentrification (positive NCI) models of neighborhood change. The study differentiates between an initial effect of new …
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Epithermal neutron activation analysis of short-lived radionuclides using a pneumatic transport system and a pulsed D-T neutron generator
… activity in parenthesis are: 21.82±3.71 (49.36 nCi/g), 279.21±27.80 (158.91 nCi/g), and 48.51±12.58 (504.78 nCi/g) respectively. These experimental half-lives agree with the published half-lives. The Monte Carlo N-Particle (MCNP) radiation transport code was used to model the graphite pile, the …
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Effects of vitamin D on inflammation and oxidative stress in airway epithelial cells
… human airway epithelial cell lines A549, NCI-H292, 16HBE14o- and primary human small airway epithelial cells were shown to express similar inflammatory mediators, with the 16HBE14o- cells shown to be a useful model of primary cells. Vitamin D significantly modulated IL-6 mRNA and protein …
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Micromechanical Simulation of Fatigue in Nodular Cast Iron
… thesis, fatigue behavior of nodular cast iron (NCI) is investigated using micromechanical simulations. An elastic-plastic porous material experiences an increase in a void volume fraction with each cycle of loading. This is called void ratchetting. The hypothesis of this thesis is to explain the …
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Computational Studies Of Enzymatic Reactions And Inorganic Compounds
… way is highly instructive. The combined ELF/NCI analysis meets the demand. In this dissertation, we have discussed the applications and development of the combined ELF/NCI analysis and QM/MM method. The combined ELF/NCI analysis has been extended to study two enzymatic reactions in Chapter 2, …
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Action, intention and knowledge
… According to Non-Cognitivist Intentionalism - NCI - practical knowledge is constituted by intentions, which are not a kind of belief, just in case they are executed. NCI happily accommodates practical knowledge’s philosophically interesting features. But it is hard to see why executing an …
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Studio di nuovi approcci farmacologici in grado di inibire l'attivazione dei recettori del fattore di crescita epidermico (EGF) in linee cellulari di carcinoma polmonare non a piccole cellule (NSCLC)
… frequentemente diagnosticata e costituisce la principale causa di morte per tumore solido al mondo. E' una malattia multifattoriale che riconosce nella cancerogenesi cause ambientali e cause genetiche. L'istotipo più frequente è il carcinoma non a piccole cellule (NSCLC) che rappresenta circa il …
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Regulation der Invasion von Bronchialkarzinomzellen unterschiedlicher Differenzierung in die Basalmembran in Kokulturen und in Matrigel-Kammern
… Unterschied gegenüber den Linien EPLC 32M1 und NCI H125 keine Signifikanz aufwies, wurde ein zweidimensionales Modell verwendet, um die Frühphasen der Invasion von Tumorzellen besser vergleichen zu können. Dabei wurde die Invasionskapazität der Tumorzellen in Matrigel®-beschichteten Kammern …
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Exploring glucagon-like peptide 1-secreting L-cells as signal transducers in the microbiota-gut-brain signalling pathways
… imaging, I explored cellular activation of NCI-H716 cells in response to B. breve NCFB 2258 secretions, and ELISA was used to determine the effects of B. breve NCFB 2258 products on the secretion of GLP-1 from NCI-H716 cells. Results: Although exposure to PUFA-containing B. breve NCFB 2258 …
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An Exploratory Study of the Effects of BIS-Substituted Triazolium Bromide Salts on the Proliferation of WI-38 Lung Cells and H-1299 Lung Cancer Cells
… have been shown to have therapeutic tendencies. Moreover, present structure activity relationship (SAR) studies display a correlation in the carbon content versus cytotoxic effect. This SAR research is an exploratory project on the biological activity of the salts, Dibenzyl-benzotriazole …
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Biomedical data retrieval utilizing textual data in a gene expression database by Richard Lu, MD.
… of high-throughput gene expression sequencing and microarrays has led to a proliferation in both the amount of genomic and clinical data that is available. Descriptive textual information deposited with gene expression data in the Gene Expression Omnibus (GEO) is an underutilized resource …
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A Narrative Care Intervention to Support the Post-Cancer Treatment Transition from Primary to Follow-up Care: Analysis of Outcomes and Content
… intervention, the Narrative Care Interview (NCI), to allow participants to story their experience of being diagnosed with and treated for a primary cancer and to share their outlook on life moving forward. The NCIs goal was to support participants in constructing a cohesive narrative that …
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Der Einfluss von Adrenostatika auf die Hormonbiosynthese und die Expression des ACTH-rezeptors in boviner Nebennierenrinden-Primärkultur
… der Cortisolsekretion. Im Unterschied zu NCI-h295-Zellen, einer NN-Karzinomzelllinie, ließ sich bei der gemeinsamen Inkubation von Adrenostatika und ACTH eine deutliche Hormonsekretion der NN-Zellen nachweisen. Die auftretende methodische Probleme der Primärkultur der bovinen NNR wurde …
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The Influence of Health Concern on the Relationship between Lifestyle Activities and Cognition in the Elderly
… 4, p<0.001). In the non-cognitive impairment (NCI) group, with K-MMSE score greater than or equal to 18, only group 4 showed significantly higher K-MMSE score (p<0.001). The other groups showed no significant differences. In the cognitive impairment (CI) group, the K-MMSE score of group 3 and 4 …
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Isolation and Structure Elucidation of Cytotoxic Natural Products from the Rainforests of Madagascar and Suriname
… cytotoxic, and the National Cancer Institute (NCI) further evaluated one of the new compounds. Bark and leaf extracts from Cerbera manghas yielded a known iridoid and a known cardiac glycoside, both of which showed good bioactivity. The cytotoxicity associated with the iridoid is unprecedented, …
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UNDERSTADING THE ROLE OF PSEUDOKINASE TRB3 IN CANCER PROGRESSION AND CHEMORESISTANCE DURING METABOLIC STRESS
… with a poor survival in cancer patients. Silencing of Trb3 in A549 promoted cell growth. On the other hand, overexpression of Trb3 in NCI-H358 inhibited cell growth. The analysis of cell cycle gene profiling revealed a decrease in several genes that are essential for cell cycle progression in …
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Trends in Receipt and Timing of Multimodality Therapy in Early-Stage Pancreatic Cancer
… to community hospitals, patients treated at an NCI-designated center were more likely to receive multimodality therapy (OR 1.62, 95 % CI 1.46–1.81) and, if they received multimodality therapy, delivery of chemotherapy in the neoadjuvant compared to adjuvant setting (OR 2.82, 95 % CI 2.00–3.98). …
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