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Showing 1 to 1 of 1 for “"NBD dimerization"”.
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Single-Molecule Studies of CFTR Gating and Pharmacology
… regulated by phosphorylation- and ATP-dependent dimerization of its two nucleotide-binding domains (NBDs), but how the dimerization process is coupled to pore opening remains contested. Whereas the binding sites for therapeutic potentiators of CFTR gating are known, the mechanism by which they …