Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"NB4"”.
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Thewingless Signaling Pathway Specifies Fates in the Drosophila Embryonic CNS
… of an identified neuroblast lineage, NB4-2. Other components of the wingless signaling pathway, porcupine, dishevelled, and armadillo also positively regulate NB formation and specification. On the other hand, zeste-white 3 acts oppositely in both processes. It was further demonstrated …
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The wingless signaling pathway specifies fates in the Drosophila embryonic CNS
… of an identified neuroblast lineage, NB4-2. Other components of the wingless signaling pathway, porcupine, dishevelled, and armadillo also positively regulate NB formation and specification. On the other hand, zeste-white 3 acts oppositely in both processes. It was further demonstrated …
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MANIPULATING CELL STATES FOR LEUKAEMIA DIFFERENTIATION THERAPY USING NETWORK PHARMACOLOGY
… which induce granulocytic differentiation of the NB4 acute promyelocytic leukaemia (APL) cell line. Connectivity Map (CMAP) analysis of these TFs and their target networks identified dimaprit and mebendazole as a drug combination which induces myeloid differentiation. Alternatively, we show that …
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NLRP2 expressziójának vizsgálata különböző immortalizált sejtvonalakon
… A kísérletek során THP-1, K562, Caco2, A549, NB4, U937, Hela és MCF-7 sejtvonalakat használtunk, melyeket 6, valamint 24 órás GM-CSF és dexametazon kezeléseknek vetettük alá. A kezelt sejtekből RNS-t izoláltunk, majd RT-qPCR segítségével meghatároztuk az NLRP2 relatív expresszióját. Az …
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Differenzierungsabhängige Modulation der Zytokin- und Chemokinexpression bei humanen myeloischen Zell-Linien
… wurde anhand von drei myeloischen Zell-Linien (NB4, HL60, K562) untersucht, ob die Zyto- und Chemokinexpression durch eine Differenzierung moduliert wird. Markerzytokine für bestimmte Richtungen der Differenzierung sollten identifiziert und <br>linienspezifische Zytokin- und Chemokinprofile …
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HEM-protein regulates cell migration and asymmetric cell division during development of the ventral nerve cord in Drosophila melanogaster
… I have focused on a typical neuronal lineage, NB4-2→GMC-1→RP2/sib, in the ventral nerve cord (VNC) of the Drosophila embryo to investigate the regulation of neuronal migration and asymmetric cell division during development of the nervous system. I have discovered a migration defect of RP2 …
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EXPLORING THE PRE-LEUKEMIC PHASE OF ACUTE PROMYELOCYTIC LEUKEMIA: INSIGHTS FROM STUDIES OF SINGLE CELL ¿OMICS¿
… by PML-RAR expression identified in human NB4 APL cells was detected in our analysis of single-cell data. Notably, the signature was confined to the expanded subpopulations, despite differences in species and experimental context. This supports the idea that expanded pre-leukemic …
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Chemistry of low and medium-valent niobium complexes supported by anionic amides.
… produce a diamagnetic and tetranuclear cluster, [Nb4Cl 12Li2(THF)8] (2.2). Further reaction of [NbCl3(TMEDA)]2 or (TMEDA)3Nb2Cl 5Li (2.1) with (3,5-Me2Ph)(Ad)NLi in THF yielded the tetravalent, dinuclear and diamagnetic {[(3,5-Me2Ph)(Ad)N]Nb(3,5Me 2Ph)}2(mu-NAd)2.2(ether) (2.3). In the reaction of …
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The G-protein coupled receptor CMKLR1/ChemR23: Studies on gene regulation, receptor ligand activation, and HIV/SIV co-receptor function
… involved in cmklr1a promoter activation in mouse NB4 1A3 cells, whereas the transcription factor NFY is important for transcription of cmklr1b in mouse BV2 cells. Cmklr1a shows expression in organs such as heart and lung whereas cmklr1b is suggested to be an inducible transcript up-regulated by …