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Showing 1 to 20 of 108 for “"NAV"”.

  1. Regulation of the FGF14:Nav Interactome by a GSK-3 Centered Pathway

    … factor critical for the maintenance of the Nav complex, in neurons is controlled via a GSK-3 dependent signaling pathway (Shavkunov et al., 2013). Additionally, inhibition of GSK-3 reduces the assembly of FGF14:Nav1.2 complexes, redistributes FGF14 and Nav channels from the axonal …

    utmb Repository record for Regulation of the FGF14:Nav Interactome by a GSK-3 Centered Pathway (opens in a new tab)

  2. Factors that impact on South African REITs trading at a discount or premium to their NAV

    … a discount or premium to their net asset value (NAV), known as the NAV spread. Globally, REITs have become an increasingly popular means for investing in real estate representing 41% of the global listed property industry and reaching a total market capitalisation of US$ 1.3 trillion as at June …

    cape-town Repository record for Factors that impact on South African REITs trading at a discount or premium to their NAV (opens in a new tab)

  3. Targeting protein: protein interaction sites for drug development against voltage-gated sodium channels

    Voltage-gated sodium (Nav) channels are responsible for initiation and propagation of action potentials, which contribute to control of neuronal excitability. Malfunction of specific Nav channel isoforms is associated with a wide range of brain disorders including psychological, neurological and …

    utmb Repository record for Targeting protein: protein interaction sites for drug development against voltage-gated sodium channels (opens in a new tab)

  4. Identifying Protein Interactors of Voltage-Gated Sodium Channel Nav1.6 in Native Tissue

    Voltage-gated sodium (Nav) channels play a critical role in the initiation and propagation of action potentials in excitable cells and are involved in numerous neurological diseases such as epilepsy, neuropathic pain, and cancer. Although approved drugs targeting Nav channels are available, they …

    utmb Repository record for Identifying Protein Interactors of Voltage-Gated Sodium Channel Nav1.6 in Native Tissue (opens in a new tab)

  5. Regulation of signaling and function of the voltage-gated sodium channel complex by protein:protein interactions

    … of neuronal function, voltage-gated Na+ (Nav) channels are important targets for therapeutic development against a wide range of health conditions. Dysfunction of Nav channels in the CNS is associated with disorders ranging from neurological (i.e., epilepsy, neurodegeneration) to …

    utmb Repository record for Regulation of signaling and function of the voltage-gated sodium channel complex by protein:protein interactions (opens in a new tab)

  6. Impacto de la neumonía asociada a ventilación mecánica en el traumatismo cráneo encefálico grave

    … (medida por días de estancia y días de VM) de la NAV en un colectivo de 144 pacientes con traumatismo craneoencefálico grave. Objetivo. Investigar la influencia sobre la mortalidad y morbilidad de la neumonía nosocomial en pacientes con traumatismo craneoencefálico grave. Con los fundamentos …

    sevilla Repository record for Impacto de la neumonía asociada a ventilación mecánica en el traumatismo cráneo encefálico grave (opens in a new tab)

  7. Resultados en reducción abierta de cadera por via interna: necrosis avascular y concordancia interobservador

    … los criterios de Salter de necrosis avascular (NAV), con un seguimiento mínimo de 18 meses. Se evaluó la concordancia interobservador para la clasificación de Salter en tres ortopedistas infantiles. Resultados Se evaluaron 20 caderas en 16 pacientes a los que se realizo reducción abierta de …

    rosario Repository record for Resultados en reducción abierta de cadera por via interna: necrosis avascular y concordancia interobservador (opens in a new tab)

  8. Exploring mechanisms of inhibition and inactivation in voltage-gated sodium channels using molecular simulations

    Voltage-gated sodium (Nav) channels play a pivotal role in the conduction of electrical signals across the human body, with different subtypes expressed across excitable tissue in the brain, heart and muscle. Nav channels transiently form transmembrane pores by cycling through the closed, open and …

    aus-cath Repository record for Exploring mechanisms of inhibition and inactivation in voltage-gated sodium channels using molecular simulations (opens in a new tab)

  9. Exploring mechanisms of inhibition and inactivation in voltage-gated sodium channels using molecular simulations

    Voltage-gated sodium (Nav) channels play a pivotal role in the conduction of electrical signals across the human body, with different subtypes expressed across excitable tissue in the brain, heart and muscle. Nav channels transiently form transmembrane pores by cycling through the closed, open and …

    anu Repository record for Exploring mechanisms of inhibition and inactivation in voltage-gated sodium channels using molecular simulations (opens in a new tab)

  10. Desenlaces de las infecciones respiratorias en la unidad de cuidado intensivo de la fundación neumologica colombiana

    … (UCI). Existen dos infecciones: neumonía (NAV) y traqueobronquitis (TAV). NAV genera impacto negativo en los desenlaces de los pacientes al aumentar la morbilidad, mortalidad y los tiempos en UCI y VM, pero no se conoce el impacto de TAV. El objetivo de este estudio fue identificar si hay …

    rosario Repository record for Desenlaces de las infecciones respiratorias en la unidad de cuidado intensivo de la fundación neumologica colombiana (opens in a new tab)

  11. Sodium channel diversity in the vestibular ganglion : evidence for Nav̳1.5-like and Nav̳1.8-like currents

    Voltage-gated sodium (Nav) channels are diverse, comprising nine known mammalian subunits, which are classified pharmacologically into tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-insensitive (TTX-1) categories. The pattern of Nav channel expression shapes response properties of neurons, while …

    mit Repository record for Sodium channel diversity in the vestibular ganglion : evidence for Nav̳1.5-like and Nav̳1.8-like currents (opens in a new tab)

  12. Simultaneous DTI and rs-fMRI using the navigated diffusion sequence

    … volume acquisition (hereafter called the single nav sequence), modified to acquire BOLD resting state fMRI (rs-fMRI) data. We also investigated inserting a second 3D EPI acquisition in the middle of each DTI volume acquisition (hereafter called the double nav sequence) to increase fMRI temporal …

    cape-town Repository record for Simultaneous DTI and rs-fMRI using the navigated diffusion sequence (opens in a new tab)

  13. Factors associated to avascular necrosis of the femoral head and non-union in patients younger than 65 years old with displaced femoral neck fractures treated with reduction and internal fixation.

    … evaluados. Los pacientes que desarrollaron NAV fueron significativamente mayores y sufrieron un trauma de más baja energía que en los casos sin AVN. Ninguna variable fue asociada con la no-unión. La regresión logística determinó que sólo la edad se asoció de forma independiente a NAV. La …

    rosario Repository record for Factors associated to avascular necrosis of the femoral head and non-union in patients younger than 65 years old with displaced femoral neck fractures treated with reduction and internal fixation. (opens in a new tab)

  14. Structural and functional role of the extracellular loops and C-terminal domain of the voltage-gated sodium ion channel

    Voltage-gated sodium ion channels (Nav) are central to action potential initiation through regulating the entry of sodium ions (Na+) into excitable cells including cardiomyocytes and neurones. The α-subunit of Nav consists of four homologous domains (DI-DIV), each consisting of six transmembrane …

    cambridge Repository record for Structural and functional role of the extracellular loops and C-terminal domain of the voltage-gated sodium ion channel (opens in a new tab)

  15. The determinants of REIT franchise value : a reprise

    … defined as the Premium-to-Net Asset Value (NAV) at which most REITs trade. In broader terms, franchise value is often defined as the present value which management is expected to add in terms of net revenue growth to shareholders. A more specific definition of franchise value was presented …

    mit Repository record for The determinants of REIT franchise value : a reprise (opens in a new tab)

  16. A sensitivity study of bow variants on the distribution of sea spray in regular head seas

    Thesis (Nav. E.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 1990.

    mit Repository record for A sensitivity study of bow variants on the distribution of sea spray in regular head seas (opens in a new tab)

  17. An integrated hydrofoil and propeller design tool for Windows environment

    Thesis (Nav. E.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 1996.

    mit Repository record for An integrated hydrofoil and propeller design tool for Windows environment (opens in a new tab)

  18. Dynamic simulation of shipboard electric power systems

    Thesis (Nav. E.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 1993.

    mit Repository record for Dynamic simulation of shipboard electric power systems (opens in a new tab)

  19. Vibration reduction of marine cable systems using dynamic absorbers

    Thesis (Nav. E.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 1996.

    mit Repository record for Vibration reduction of marine cable systems using dynamic absorbers (opens in a new tab)

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