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Showing 1 to 1 of 1 for “"NATURAL SCIENCES::Chemistry::Organic chemistry"”.
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Conjugation of oligonucleotides for drug delivery via a linker derived from Meldrum’s acid and A capture-release method to synthesize long oligonucleotides
Click chemistry offers a versatile approach for linking modular units via simple chemical reactions under mild conditions, often in benign solvents. Our research explores the conjugation of biomolecules using Meldrum’s acid derivatives as linkers, facilitating the stepwise attachment of an amine …