Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"NATURAL SCIENCES::Biology::Cell and molecular biology::Molecular biology"”.
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Determining the Roles of the Aldehyde Dehydrogenase Enzymes 5 and 6 during Icewine and Table Wine Fermentation in a Commercial Wine Yeast Using CRISPR-Cas9.
… known for Icewine which is fermented from grapes naturally frozen on the vine. Grapes are harvested below –8°C and pressed while frozen, trapping ice crystals inside the berries and releasing juice highly concentrated in sugars and acids. The high sugar juice environment (40°Brix) causes …
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Regulation of Tubulin dynamics by the +Tip tracking protein Mal3
… network is a central component of the eukaryotic cell cytoskeleton. In the fission yeast S. pombe, a complex of three proteins specifically tracks MT +ends and stabilizes MTs in the cell. It is composed of the proteins Mal3, Tip1 and Tea2. Mal3, the S. pombe homologue of EB1, is a highly conserved …
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Physiological Oxygen and Media Conditions Influence Breast Cancer Hallmarks in Vitro
Standard cell culture conditions often fail to replicate the in vivo microenvironment, limiting the reproducibility and physiological relevance of experimental findings. For example, commonly used media such as Dulbecco’s Modified Eagle Medium (DMEM) contain supraphysiological levels of key …
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Investigating β- and γ-secretase function and processing of APP with genetic and pharmacological tools
… of Amyloid Precursor Protein (APP) by BACE1 and the gamma secretase complex (γS) generates amyloid-beta (Aβ), a small peptide that is highly implicated in the pathogenesis of Alzheimer’s Disease. Despite decades of research, there remains a lack of understanding of the endogenous functions of …