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Showing 1 to 1 of 1 for “"NASPER"”.
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Nucleic Acid Scaffold-dependent Proximity-mediated Enzyme Response (NASPER) - A Proof of Concept Study
… cells. The approach proposed in the thesis (NASPER), aims to target cells overexpressing hTERT RNA and cause their apoptosis, preventing this evolution and debulking the tumour mass. NASPER involves bringing two fusion proteins, each of which comprises a custom-designed PUF (Pumilio and FBF) …