Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"NADH oxidation"”.
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Structural and functional studies of mitochondrial NADH:ubiquinone oxidoreductase (complex I)
NADH:ubiquinone oxidoreductase (complex I) is the largest and most complicated enzyme in the mitochondrial electron transfer chain. It catalyses the oxidation of NADH and the reduction of ubiquinone, coupled to the translocation of protons across the mitochondrial inner membrane, maintaining the …
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Characterization of Solution Species Relevant to the Peroxidase-Nadh Biochemical Oscillator
The discovery of significance of iron-NADH complexation for the kinetics of NADH decomposition and oxidation led to an investigation of the influence of solution oxygen and biologically prominent metal ions on NADH degradation. Almost all metal ions under investigation appeared to complex quickly …
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Structure-function studies of respiratory complex I from Paracoccus denitrificans using membrane mimetics
Respiratory complex I (NADH:ubiquinone oxidoreductase) is a crucial metabolic enzyme that couples the free energy released from NADH oxidation and ubiquinone reduction to translocate four protons across energy-transducing membranes, contributing to the proton motive force that powers oxidative …
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Biofuel Cell Anode for NAD-Dependent Enzymes
… several carbon-to-carbon bonds which make their oxidation processes significantly more complex than those of hydrogen. Examples of these biofuels are sugars and alcohols. If we refer back to nature, we have learned that enzymes play a very important role in oxidizing these types of fuels to …
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Investigating the rate-limiting step of mitochondrial complex I catalysis
Respiratory complex I (NADH:ubiquinone oxidoreductase) is a key enzyme in metabolism and is the least understood protein in the mitochondrial electron transfer chain (ETC). It couples the energy released from NADH oxidation and ubiquinone (Q) reduction to the translocation of four protons across …
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Paracoccus denitrificans as a model system for studying the mechanism of respiratory complex I
Respiratory complex I (NADH:ubiquinone oxidoreductase) is a crucial metabolic enzyme that couples the free energy released from NADH oxidation and ubiquinone reduction to the translocation of four protons across an energy-transducing membrane, contributing to the proton motive force used to …
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Cryo-EM studies of substrate and inhibitor binding to mammalian respiratory complex I
Mammalian respiratory complex I (NADH:ubiquinone oxidoreductase) is an intricate multi-subunit, energy-transducing membrane protein that is essential for aerobic energy metabolism and NADH/NAD⁺ homeostasis. It couples the energy released from NADH oxidation and ubiquinone (Q) reduction to pump four …
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Biochemical characterization of respiratory chain flavoproteins
… to the electron transport chain: • The type 2 NADH dehydrogenase (NDH-2) from Streptococcus agalactiae • The sulfide:quinone oxidoreductase (SQR) from the archaeon Caldivirga maquilingensis • The NDH-2 from Thermus thermophilus, now re-classified as a coenzyme A disulfide reductase (CoADR) …
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Kinetic studies of redox and related reactions of some new isoalloxazines
… for reactions with 1,3-dithio-2-propanol, with NADH and with sulphite. In the case of the dithiopropanol reaction, a linear free-energy relationship was observed between the logarithm of the second order rate constant and the polarographic half-wave potential, E⅟₂ (slope 26 ± 1 V⁻¹). The …
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Intensified biocatalysis for production of fuel and chemicals from lipids.
Triglycerides are abundant biorenewable resources found in vegetable oils and fats. The effective utilization of triglycerides is one of the key interests in developing renewable fuels and products. However, triglycerides are difficult and inefficient to be used as fuels directly in regular …