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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 236 for “"NADH"”.
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Az alternatív NADH dehidrogenázok szerepe a fonalas gombákban
… légzési útvonal egy enzimjét, az alternatív NADH dehidrogenázt mutatja be. Továbbá körüljárja azt a kérdést, hogy az oxigénből képződő stresszorok megjelenése, vagy az alternatív enzimek működése kedvezőbb-e bioipari szempontból.
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Anaerobic, NADH-Dependent Haem Breakdown in a Family of Haemoproteins
… anaerobically using 'nature's reductant', NADH, and the $\textit{Yersinia enterocolitica}$ protein, HemS. To study the features of this reaction in more detail, conventional experimental methods were combined with Energy Landscape Theory. Deuterium labelling demonstrated that the reaction …
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Characterization of Solution Species Relevant to the Peroxidase-Nadh Biochemical Oscillator
The discovery of significance of iron-NADH complexation for the kinetics of NADH decomposition and oxidation led to an investigation of the influence of solution oxygen and biologically prominent metal ions on NADH degradation. Almost all metal ions under investigation appeared to complex quickly …
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Preparation of a self-contained NADH co-factor recycling particle system
… Since glucose dehydrogenase (GDH) and NADH oxidase, are industrially relevant co-factor recycling enzymes for NAD(P)H and NAD+ respectively, characterisation of their immobilisation is of interest. The current work describes the use of the proprietary particle technology, termed ReSyn™, …
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Characterization of the particulate and soluble respiratory NADH dehydrogenase of pig liver
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The demonstration, characterization and partial purification of a peroxidase and NADH oxidase in uterine tissue
Call number: LD2668 .T4 1966 N631
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Experimental and theoretical studies of the peroxidase-NADH biochemical oscillator: An enzyme-mediated chemical switch
Made available in DSpace on 2011-05-07T12:56:43Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9512502.pdf: 11198055 bytes, checksum: f9d94b0c62964b89c1d9318b1cbc8386 (MD5) Previous issue date: 1994
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I. Rates of thiol-disulfide interchange reactions involving proteins. II. regeneration of the nicotinamide cofactor NADH
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 1981
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Characterization of alternative NADH dehydrogenases in the respiratory chain of Toxoplasma gondii as a novel drug targets
… mit Hilfe der RT-PCR überprüft: (i) Alternative NADH Dehydrogenase I und II; (ii) die Flavoprotein Untereinheit der Succinat-Dehydrogenase; (iii) Cytochrom c1; und (iv) die ß-Untereinheit der ATP-Synthase. Diese Gene zeigen höchste Übereinstimmungen zu Orthologen in Plasmodium. Sie sind …
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Chemiluminescence detection of NADH and enzyme substrates with immobilized tris(2,2'-bipyridyl)ruthenium (II) and dehydrogenase enzymes
… employ NAD$\sp+$ as their cofactor and produce NADH in an amount equivalent to reacted analyte. Detection of NADH via the ECL reaction with Ru(bpy)$\sb3\sp{3+}$ is then used to determine analyte concentration.
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Biochemical Characterization of <i>Toxoplasma gondii</i> Type II NADH Dehydrogenases - Physiological Impact on Mitochondrial Functions and Energy Metabolism
The single subunit mitochondrial type II NADH dehydrogenases (NDH2s) in apicomplexan parasites have been considered as potential drug targets due to the absence in mammalian cells. Toxoplasma gondii encodes two isoforms of NDH2s, TgNDH2-I and TgNDH2-II, whose functions are not known. Therefore, …
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Metabolic-response assessment of metastatic murine breast cancer in 2D and 3D cultures using intrinsic NADH as a natural biomarker
… the reduced nicotinamide adenine dinucleotide (NADH) in metastatic murine breast cancer cells 4T1. In addition, we investigated the cellular metabolic response of 4T1 cells in 2D monolayer and 3D collagen matrix cultures to drug treatment using two novel metabolic drugs, namely MD1 and TPPBr. …
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Control of Cellular Redox State and Biomass Synthesis
… the cellular redox state, measured by the NAD+/NADH ratio, can constrain the synthesis of oxidized biomass. This dissertation aims to uncover the determinants of the cellular NAD+/NADH ratio and how the cellular redox state governs biosynthetic capabilities of cancer cells in response to …
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Investigating xanthine oxidase toxicity models in cultured cerebellar granule neurons
… the reduced nicotinamide adenine dinucleotide (NADH) in cell cultures is much less studied. NADH is another oxidizable substrate for XOR that binds to a different site on the enzyme from that of X binding. The aim of this project was to investigate some aspects of the in vitro toxicity of XOR, …
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Studies on the metabolism of polyhydroxyalkanoic acid and phosphate in the biological excess phosphate removal process
… which would be expected to affect the level of NADH. Despite previous correlation between PHA storage and phosphate sequestering, it was found that even with good PHA storage in the anaerobic condition some sludges showed poor phosphate uptake in the corresponding aerobic condition. PHA …
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Thermodynamics of Ligand Binding to Glutamate Dehydrogenase
… discovered a 40-year-old sequence error at the NADH/ADP/ECG binding site. Residue 387 was mistakenly identified as asparagine rather than the correct amino acid identity, lysine. The free energy penalty for the endogenous NADH ligand binding at the site having the incorrect residue was +5 …
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Studies of Enzyme Kinetics and Inhibition Through Capillary Electrophoretic Enzyme Assays
… this dissertation use fluorescence detection of NADH to study enzymes that utilize NAD+/NADH as a cofactor. Several methods for studying the kinetics of two dehydrogenase enzymes as well as their inhibition by monitoring NADH fluorescence are utilized. Variations of EMMA will be presented, …
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